Pain Research Forum

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May 18 2015
D1/D5 receptor signaling regulates maintenance of pain memory trace
news Research
May 13 2015
A recent PRF webinar highlighted the relevance of epigenetics to understanding chronic pain mechanisms and vulnerability and developing new analgesics
news Conferences | Research
May 07 2015
First large, rigorous trial finds no effect on pain or disability measures
news Research
Apr 21 2015
Findings from nerve injury model recapitulate clinical observations, implicate noradrenergic system
news Research

Papers of the Week

Community & Resource Updates

US National Vulvodynia Association
Presbyterian College School of Pharmacy
Clinton, South Carolina, US

Community Updates Lower block

Forums

May 27 2015

Investigators agree that both males and females should be included in preclinical studies, but should the National Institutes of Health...

discussion
May 25 2015

PRF will host a webinar with Cheryl Stucky, Medical College of Wisconsin, Milwaukee, US, on Tuesday, June 16, at 12:00-1:30 p.m...

webinar

Recent Comments

May 29 2015
Although a number of mechanisms have been identified for the transduction...
Paper
May 18 2015
Ted Price and his collaborators have uncovered an important new role for...
News
Apr 29 2015
This is an elegant study from Rohini Kuner’s group at the University...
Paper
Apr 23 2015
Thanks for this great interview with Claudia Sommer.  We did a review of...
Interview
Apr 21 2015
This is a landmark paper for the field. As Mark Hoon nicely commented,...
Paper
Apr 21 2015
This is a very nice study showing that A3 adenosine receptor activation...
Paper
Apr 20 2015
Pungency Receptor Structure Reveals Some, But Not All, of Its Mysteries We...
Paper
Apr 15 2015
The transient receptor potential channel vanilloid type 1 (TRPV1) is...
Paper
Apr 03 2015
In this interesting paper, the authors experimentally identify a model by...
News
Mar 30 2015
By: Qiufu Ma
Exactly 50 years ago, Melzack and Wall proposed the gate control theory of...
News
Mar 23 2015
This elegant study results from a perfect collaboration between two well-...
Paper
Feb 24 2015
This comment was co-authored by David Ritter, Benjamin Zemel, and Angelo...
Paper
Feb 24 2015
At least half of people with spinal cord injury (SCI) experience chronic...
Paper
Feb 13 2015
Chronic pain is commonly associated with depressive mood. Conversely,...
Paper
Feb 09 2015
NEO6860, a “Modality-Specific” TRPV1 Antagonist: An Elegant...
Discussion
Jan 26 2015
By: Rob Boell
A particularly useful systematic review that includes statistical analysis...
Paper
Jan 21 2015
This comment was co-authored by Marta Ceko, National Center for...
News
Jan 20 2015
This study provides in vivo evidence for reactive glial cells in the...
News
Jan 05 2015
By: Mark Hoon
How many different types of somatosensory neurons are there? It has been...
Paper
Dec 22 2014
This comment was coauthored by Tor Wager. We thank the Pain Research Forum...
Journal Club
Dec 19 2014
Perl Memorial Lecture to honor the life and work of Dr. Edward Perl,...
Discussion
Dec 11 2014
This work has now been published:  Piezo2 is the major transducer of...
Blog
Nov 21 2014
I really like this new paper from Lavanya Moparthi and colleagues that...
Paper
Nov 03 2014
The study by Zhang et al. is exciting to me for two reasons. One is that...
News
Nov 03 2014
I read the paper by Dr. Zhang et al. with great interest. They showed IGF-...
News

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Research Resources

Information for the new researcher or veteran in the field, Pain 101 is our growing collection of topical articles on important issues in pain research. Check out our articles on modeling pain in lower organisms, the role of glia in chronic pain, and transcranial magnetic stimulation. Our Pain Genes Resource will have the most up-to-date information on the genetics of pain sensitivity, risk of chronic pain and response to analgesics, presented in a format that makes it easy to keep current. We're in the process of pulling together data on the first  53 genes—you can help this resource grow by submitting new genes and studies. Stay tuned for more resources to come, including our Drug Pipeline database.