Feb 21 2017
Findings point the way toward a clinical strategy to mitigate an adverse effect of opioids
news Research
Feb 16 2017
New findings suggest a possible strategy to curb opioid side effects in patients while maintaining analgesia
news Research
Feb 13 2017
Machine learning finds brain activity differs in low and high pain states during chronic low back pain
news Conferences | Research
Feb 06 2017
New compound boosts endogenous cannabinoids to alleviate pain
news Conferences | Research

Papers of the Week

Community & Resource Updates

23 Feb 2017 to 26 Feb 2017
Atlanta, Georgia, US
Abstract Submission Deadline:
30 Sep 2016
Registration Deadline:
31 Jan 2017
* State of the Art Lecture by Allan Basbaum
Massachusetts General Hospital/Harvard Medical School
Boston, Massachusetts, US

Community Updates Lower block


Jan 10 2017

Editor's Note: Three young investigators were honored with awards at the International Association for the...

Dec 12 2016

On Decemver 12, Brian Schmidt gave a talk on the mechanisms of cancer pain. After his talk, there was a panel discussion...


Recent Comments

Jan 30 2017
I agree with Michael Gold’s comments pointing out that to accept the...
Jan 24 2017
Thank you for the publication and thanks to others for this lively...
Jan 22 2017
There are, of course, responses to all of the points Wood and Emery raised...
Jan 20 2017
Shades of Ramon y Cajal vs. Golgi! And once again, both Drs. Gold and Wood...
Jan 19 2017
By: John Wood
Editor’s note: This comment, written in response to Michael Gold...
Jan 19 2017
Okay―I admit it; it was the PRF tweet [announcing publication of the PRF...
Nov 11 2016
So, the big question I have is this. If this were true, and pervasive,...
Oct 21 2016
To better treat pain, we require an understanding of the molecular...
Jul 26 2016
The new work reported by Rebecca Seal and colleagues indeed represents a...
Jul 11 2016
In my opinion the first line of the sixth paragraph in Part 2 is key in...
Jun 07 2016
Pain in infancy can have lifelong effects. In rodents, tissue injury in a...
May 29 2016
An interesting article which concludes that relief of pain by itself is...
May 16 2016
While several studies have previously demonstrated a role for the...
Mar 28 2016
Migraine is the third most common disease on Earth and the eighth most...
Mar 07 2016
By: PRF Team
Editor's Note: The work, described above, from Cobi Heijnen and...
Feb 01 2016
By: PRF Team
UPDATE: NEOMED has received approval from Health Canada to begin a phase...
Jan 27 2016
I tend to agree with comments from both of the above commenters. A large...
Q & A
Jan 26 2016
The debate is still ongoing. After the criticisms by Davis et al. on...
Jan 13 2016
An elegant paper by Xu et al. reports a potential new strategy to treat...
Dec 23 2015
Among the three main sodium channel alpha subunits present in nociceptors...
Nov 19 2015
I agree with Dr. Bhagat: for local anesthetics to block voltage-gated...
Q & A
Nov 12 2015
Local anesthetics are the backbone for any dental treatment. The effects...
Q & A
Nov 02 2015
I have only had experience using three-chambered conditioned place...
Q & A
Nov 02 2015
I have done place preference experiments in both types of boxes over the...
Q & A
Oct 19 2015
This comment was co-authored by Michael Fleming, University of...

Members & Community

PRF members have full access to other members' profiles and can contact colleagues through the site. If you are not a member yet, it's free and easy to join the only web community dedicated to pain research.


Becoming a PRF member demonstrates your support for the Pain Research Forum and will contribute to the site's long-term success.

Research Resources

Information for the new researcher or veteran in the field, Pain 101 is our growing collection of topical articles on important issues in pain research. Check out our articles on modeling pain in lower organisms, the role of glia in chronic pain, and transcranial magnetic stimulation. Our Pain Genes Resource will have the most up-to-date information on the genetics of pain sensitivity, risk of chronic pain and response to analgesics, presented in a format that makes it easy to keep current. We're in the process of pulling together data on the first  53 genes—you can help this resource grow by submitting new genes and studies. Stay tuned for more resources to come, including our Drug Pipeline database.