News

Jul 06 2015
Novel inhibitor aimed at enzyme in tetrahydrobiopterin pathway reduces pain in neuropathic, inflammatory models without adverse effects
news Drug Development | Research
Jul 02 2015
Mouse study finds that a drug targeting MOR splice variant relieves pain without usual opioid side effects
news Drug Development | Research
Jun 26 2015
Mining the sleep-pain connection for new therapeutic strategies
news Conferences | Research
Jun 26 2015
Keratinocytes emerge as active players in sensing pain
news Conferences | Research

Papers of the Week

Community & Resource Updates

7 Jul 2015 to 11 Jul 2015
Rio de Janeiro, Brazil
Abstract Submission Deadline:
13 Mar 2015
Alert:
Registration is now open.
Rush University Medical Center
Chicago, Illinois, US

Community Updates Lower block

Forums

Jun 16 2015

On June 16, Cheryl Stucky, Medical College of Wisconsin, Milwaukee, US, gave a talk describing the problem of sickle cell pain,...

webinar
May 27 2015

Investigators agree that both males and females should be included in preclinical studies, but should the National Institutes of Health...

discussion

Recent Comments

Jun 26 2015
Since the 1970s, researchers have detected an increasing variety of neural...
News
Jun 26 2015
By: Ted Price
While ERK is a well-known contributor to pain sensitization, isoform and...
Paper
Jun 22 2015
This study by Nicol et al. uncovers a novel player, G protein receptor 84...
Paper
Jun 12 2015
In addition to this report, an elegant study co-led by Greg Neely and...
News
Jun 08 2015
This is an interesting study that is worth attention. Mindfulness...
Paper
May 29 2015
Although a number of mechanisms have been identified for the transduction...
Paper
May 18 2015
Ted Price and his collaborators have uncovered an important new role for...
News
Apr 29 2015
This is an elegant study from Rohini Kuner’s group at the University...
Paper
Apr 23 2015
Thanks for this great interview with Claudia Sommer.  We did a review of...
Interview
Apr 21 2015
This is a landmark paper for the field. As Mark Hoon nicely commented,...
Paper
Apr 21 2015
This is a very nice study showing that A3 adenosine receptor activation...
Paper
Apr 20 2015
Pungency Receptor Structure Reveals Some, But Not All, of Its Mysteries We...
Paper
Apr 15 2015
The transient receptor potential channel vanilloid type 1 (TRPV1) is...
Paper
Apr 03 2015
In this interesting paper, the authors experimentally identify a model by...
News
Mar 30 2015
By: Qiufu Ma
Exactly 50 years ago, Melzack and Wall proposed the gate control theory of...
News
Mar 23 2015
This elegant study results from a perfect collaboration between two well-...
Paper
Feb 24 2015
This comment was co-authored by David Ritter, Benjamin Zemel, and Angelo...
Paper
Feb 24 2015
At least half of people with spinal cord injury (SCI) experience chronic...
Paper
Feb 13 2015
Chronic pain is commonly associated with depressive mood. Conversely,...
Paper
Feb 09 2015
NEO6860, a “Modality-Specific” TRPV1 Antagonist: An Elegant...
Discussion
Jan 26 2015
By: Rob Boell
A particularly useful systematic review that includes statistical analysis...
Paper
Jan 21 2015
This comment was co-authored by Marta Ceko, National Center for...
News
Jan 20 2015
This study provides in vivo evidence for reactive glial cells in the...
News
Jan 05 2015
By: Mark Hoon
How many different types of somatosensory neurons are there? It has been...
Paper

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Research Resources

Information for the new researcher or veteran in the field, Pain 101 is our growing collection of topical articles on important issues in pain research. Check out our articles on modeling pain in lower organisms, the role of glia in chronic pain, and transcranial magnetic stimulation. Our Pain Genes Resource will have the most up-to-date information on the genetics of pain sensitivity, risk of chronic pain and response to analgesics, presented in a format that makes it easy to keep current. We're in the process of pulling together data on the first  53 genes—you can help this resource grow by submitting new genes and studies. Stay tuned for more resources to come, including our Drug Pipeline database.