Post-surgical contributors to persistent knee pain following knee replacement: The Multicenter Osteoarthritis Study (MOST).

Source: Osteoarthr Cartil Open 2023 Mar; 5(1). doi: 10.1016/j.ocarto.2023.100335Authors: Aoyagi K, Law LF, Carlesso L, Nevitt M, Lewis CE, Wang N, Neogi T

Pain persistence following knee replacement (KR) occurs in ∼20-30% of patients. Although several studies have identified preoperative risk factors for persistent post-KR pain, few have focused on post-KR contributing factors. We sought to determine whether altered nociceptive signaling and other peripheral nociceptive drivers present post-operatively contribute to post-KR pain.

Pubmed ID: https://pubmed.ncbi.nlm.nih.gov/36798734/

Paper chosen by Rebecca Seal

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