Mechanism of Aspirin oxidative stress regulating interleukin-induced apoptosis in nucleus pulposus cells in a rat model of intervertebral disc degeneration.
PAPERS | February 18-24, 2023 | |
Source: Ann Transl Med 2023 Jan 31; 11(2). doi: 10.21037/atm-22-5700Authors: Liang H, Shi H, Li Y, Wang D, Zhang Y
Intervertebral disc degeneration (IDD) is an important cause of low back pain. Increase of reactive oxygen species (ROS), overexpression of inflammatory factors, and loss of extracellular matrix are important factors in the pathological changes of IDD. The present study aimed to investigate the mechanism of action of Aspirin regulating oxidative stress in IDD, so as to propose new treatment.
Pubmed ID: https://pubmed.ncbi.nlm.nih.gov/36819489/