ISSLS Prize in Bioengineering Science 2023: Age- and sex-related differences in lumbar intervertebral disc degeneration between patients with chronic low back pain and asymptomatic controls.

Source: Eur Spine J 2023 Feb 18; . doi: 10.1007/s00586-023-07542-6Authors: Bonnheim NB, Lazar AA, Kumar A, Akkaya Z, Zhou J, Guo X, O’Neill C, Link TM, Lotz JC, Krug R, Fields AJ

Clinical management of disc degeneration in patients with chronic low back pain (cLBP) is hampered by the challenge of distinguishing pathologic changes relating to pain from physiologic changes related to aging. The goal of this study was to use imaging biomarkers of disc biochemical composition to distinguish degenerative changes associated with cLBP from normal aging.

Pubmed ID: https://pubmed.ncbi.nlm.nih.gov/36805320/