Up-Regulation of ProBDNF/p75 Signaling in Spinal Cord Drives Inflammatory Pain in Male Rats.
PAPERS | January 14-20, 2023 | |
Source: J Inflamm Res 2023; 16. doi: 10.2147/JIR.S387127Authors: Li H, Liu T, Sun J, Zhao S, Wang X, Luo W, Luo R, Shen W, Luo C, Fu D
The spinal cord expresses brain-derived neurotrophic factor precursor (proBDNF) and its receptor pan neurotrophin receptor 75 (p75). However, the role of spinal proBDNF signaling in the pathogenesis of inflammatory pain remains unknown.
Pubmed ID: http://www.ncbi.nlm.nih.gov/pubmed/36643954?dopt=Abstract