Phenotype- and species-specific skin proteomic signatures for incision-induced pain in humans and mice.

Source: Br J Anaesth 2023 Jan 04; . doi: 10.1016/j.bja.2022.10.040Authors: Segelcke D, van der Burgt M, Kappert C, Schmidt Garcia D, Sondermann JR, Bigalke S, Pradier B, Gomez-Varela D, Zahn PK, Schmidt M, Pogatzki-Zahn EM

Acute pain after surgery is common and often leads to chronic post-surgical pain, but neither treatment nor prevention is currently sufficient. We hypothesised that specific protein networks (protein-protein interactions) are relevant for pain after surgery in humans and mice.

Pubmed ID: http://www.ncbi.nlm.nih.gov/pubmed/36609060?dopt=Abstract

Paper chosen by Rebecca Seal

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