June 6-12, 2025
Showing 1-25 of 32.
Modulation of miR-145 in a mouse model of multiple sclerosis: A promising approach to attenuate inflammation and degeneration
Source: Neurobiology of disease Authors: Monique Marylin Alves de Almeida, Samantha F Kornfeld, Yves De Repentigny, Majd Al-Aarg, Ibrahim Ghani, Sarah E Cummings, Emma R Sutton, Rebecca Yaworski, Kelsea S McKay, Sabrina Gagnon, Ariane Beauvais, Rashmi Kothary, Publication Date: Thu, 12 Jun 2025 06:00:00 -0400…
Glycine receptor and release site organization impacts the kinetics of glycinergic synapse currents
Source: Biophysical journal Authors: Ronel Elbaz, Yarden Levinsky, Limor Freifeld, Publication Date: Fri, 13 Jun 2025 06:00:00 -0400 Biophys J. 2025 Jun 11:S0006-3495(25)00367-4. doi: 10.1016/j.bpj.2025.06.007. Online ahead of print. ABSTRACT Glycinergic synapses are the most abundant inhibitory synapses in the brain-stem and spinal cord and…
A lasting impression
Source: eLife Authors: Rochelle Ackerley, Roger H Watkins, Publication Date: Fri, 13 Jun 2025 06:00:00 -0400 Elife. 2025 Jun 13;14:e107620. doi: 10.7554/eLife.107620. ABSTRACT Touch-sensitive neurons in the fingertips take previous physical contacts into account when relaying tactile information to the brain. PMID:40511665 | PMC:PMC12165689 |…
Fingertip viscoelasticity enables human tactile neurons to encode loading history alongside current force
Source: eLife Authors: Hannes P Saal, Ingvars Birznieks, Roland S Johansson, Publication Date: Fri, 13 Jun 2025 06:00:00 -0400 Elife. 2025 Jun 13;12:RP89616. doi: 10.7554/eLife.89616. ABSTRACT Human skin and its underlying tissues constitute a viscoelastic medium, implying that any deformation depends not only on the…
Efficacy and safety of drug combinations for chronic pelvic pain: a systematic review
Source: Pain reports Authors: Mohammed Mohiuddin, Rex Park, Ursula Wesselmann, Caroline Pukall, Keith Jarvi, J Curtis Nickel, R Christopher Doiron, Sandra Halliday, Ian Gilron, Publication Date: Tue, 17 Jun 2025 06:00:00 -0400 Pain Rep. 2025 Jun 13;10(4):e1299. doi: 10.1097/PR9.0000000000001299. eCollection 2025 Aug. ABSTRACT Clinical disorders…
Environmental microbiomes drive chemotactile sensation in octopus
Source: Cell Authors: Rebecka J Sepela, Hao Jiang, Yern-Hyerk Shin, Tessa L Hautala, Jon Clardy, Ryan E Hibbs, Nicholas W Bellono, Publication Date: Wed, 18 Jun 2025 06:00:00 -0400 Cell. 2025 Jun 9:S0092-8674(25)00620-8. doi: 10.1016/j.cell.2025.05.033. Online ahead of print. ABSTRACT Microbial communities coat nearly every…
EXPRESS: Preoperative reactive oxygen species exacerbate postoperative hyperalgesia by aggravating neuroinflammation through galectin-3
Source: Molecular pain Authors: Xuemei Zheng, Bin Shu, Ai Yan, Yonggang Liang, Niannian Huang, Houping Wang, Weilong Hong, Yongqin Chen, He Huang, Guangyou Duan, Publication Date: Fri, 13 Jun 2025 06:00:00 -0400 Mol Pain. 2025 Jun 13:17448069251353026. doi: 10.1177/17448069251353026. Online ahead of print. ABSTRACT Patients…
ACOG Issues Pain Management Guidelines for IUD Insertion, Other Procedures
Source: JAMA Authors: Samantha Anderer, Publication Date: Fri, 13 Jun 2025 06:00:00 -0400 JAMA. 2025 Jun 13. doi: 10.1001/jama.2025.7805. Online ahead of print. NO ABSTRACT PMID:40512479 | DOI:10.1001/jama.2025.7805 Pubmed ID: pubmed:40512479 Identifiers: pmid:40512479, doi:10.1001/jama.2025.7805,
Neural substrates of cold nociception in Drosophila larva
Source: eLife Authors: Atit A Patel, Albert Cardona, Daniel N Cox, Publication Date: Fri, 13 Jun 2025 06:00:00 -0400 Elife. 2025 Jun 13;12:RP91582. doi: 10.7554/eLife.91582. ABSTRACT Metazoans detect and differentiate between innocuous (non-painful) and/or noxious (harmful) environmental cues using primary sensory neurons, which serve as…
Presynaptic mu opioid receptors suppress the functional connectivity of ventral tegmental area dopaminergic neurons with aversion-related brain regions
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience Authors: Yichen Wu, Tamara Perez-Rosello, Rajeshwar Awatramani, D James Surmeier, Publication Date: Fri, 13 Jun 2025 06:00:00 -0400 J Neurosci. 2025 Jun 13:e1194242025. doi: 10.1523/JNEUROSCI.1194-24.2025. Online ahead of print. ABSTRACT Opioid…
Impaired plasma membrane calcium ATPase activity and mitochondrial dysfunction contribute to calcium dysregulation in Fabry disease-related painful neuropathy
Source: Neurobiology of disease Authors: Francesco Formaggio, Asia Pizzi, Cecilia Delprete, Davide Pasqualini, Isabella Mataloni, Roberto Rimondini, Ludovica Campolongo, Vincenzo Donadio, Anna Maria Ghelli, Rocco Liguori, Marco Caprini, Publication Date: Sat, 14 Jun 2025 06:00:00 -0400 Neurobiol Dis. 2025 Jun 12:107000. doi: 10.1016/j.nbd.2025.107000. Online ahead…
Internal models in active self-motion estimation: role of inertial sensory cues
Source: Journal of neurophysiology Authors: Milou J L van Helvert, Luc P J Selen, Robert J van Beers, W Pieter Medendorp, Publication Date: Sat, 14 Jun 2025 06:00:00 -0400 J Neurophysiol. 2025 Jun 14. doi: 10.1152/jn.00281.2024. Online ahead of print. ABSTRACT Self-motion estimation is thought…
Establishing the patient acceptable symptom state for patient-reported pain outcomes 6 months after breast cancer surgery
Source: Pain reports Authors: Matthew Kang, David Rice, Nuala Helsby, Andrew Somogyi, Michal Kluger, Daniel Chiang, Publication Date: Tue, 17 Jun 2025 06:00:00 -0400 Pain Rep. 2025 Jun 13;10(4):e1297. doi: 10.1097/PR9.0000000000001297. eCollection 2025 Aug. ABSTRACT INTRODUCTION: The patient-acceptable symptom state (PASS) is a threshold score…
Transcutaneous stimulation of the cervical spinal cord facilitates motoneuron firing and improves hand-motor function after spinal cord injury
Source: Journal of neurophysiology Authors: Nikhil Verma, Jeonghoon Oh, Ernesto Bedoy, Nikole Chetty, Alexander G Steele, Seo Jeong Park, Jaime R Guerrero, Amir H Faraji, Douglas Weber, Dimitry G Sayenko, Publication Date: Tue, 10 Jun 2025 06:00:00 -0400 J Neurophysiol. 2025 Jun 10. doi: 10.1152/jn.00422.2024….
Phospho-CREB regulation on NMDA glutamate receptor 2B and mitochondrial calcium uniporter in the ventrolateral periaqueductal gray controls chronic morphine withdrawal in male rats
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience Authors: Hyun Yi, Jun Gu, Peter J Hamilton, Shue Liu, Shoumin Zhu, Daigo Ikegami, Kentaro Hayashi, Yuta Kashiwagi, Takafumi Iida, Qiaofeng Liu, Xun Zhu, Xiaoying Tong, Dunfa Peng, Gerald Z Zhuang,…
Retinoic acid breakdown is required for proximodistal positional identity during axolotl limb regeneration
Source: Nature communications Authors: Timothy J Duerr, Melissa Miller, Sage Kumar, Dareen Bakr, Jackson R Griffiths, Aditya K Gautham, Danielle Douglas, S Randal Voss, James R Monaghan, Publication Date: Tue, 10 Jun 2025 06:00:00 -0400 Nat Commun. 2025 Jun 10;16(1):4798. doi: 10.1038/s41467-025-59497-5. ABSTRACT Regenerating limbs…
Causal associations between genetically predicted placental weight and migraine
Source: Headache Authors: Chung-Chih Liao, Chun-I Lee, Yi-Chun Huang, Ke-Ru Liao, Jung-Miao Li, Publication Date: Wed, 11 Jun 2025 06:00:00 -0400 Headache. 2025 Jun 11. doi: 10.1111/head.14977. Online ahead of print. ABSTRACT BACKGROUND: Placental weight (PW) is a crucial factor in fetal development, influencing various…
Drebrin Upregulation Regulates Astrocyte Polarization and Supports Tissue Recovery After Spinal Cord Injury in Mice
Source: Glia Authors: Barbora Smejkalová, Marta Ornaghi, Kateřina Štěpánková, Juliane Schiweck, Lucia Machová Urdzíková, Robert Huelse, Susanne Mueller, Philipp Boehm-Sturm, Jessica C F Kwok, James Fawcett, Kai Murk, Britta J Eickholt, Pavla Jendelová, Publication Date: Wed, 11 Jun 2025 06:00:00 -0400 Glia. 2025 Jun 11….
FOXP3+ Macrophage-Derived Amphiregulin Promotes White Matter Repair of Experimental Autoimmune Encephalomyelitis
Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology Authors: Shilin Wu, Shishi Shen, Wenxuan Sun, Yipeng Zhao, Jiaqi Zhang, Zihong Wang, Wei Cai, Zhengqi Lu, Wei Qiu, Publication Date: Wed, 11 Jun 2025 06:00:00 -0400 FASEB J. 2025…
Iterative transcription factor screening enables rapid generation of microglia-like cells from human iPSC
Source: Nature communications Authors: Songlei Liu, Li Li, Fan Zhang, Mariana Garcia-Corral, Katharina Meyer, Patrick R J Fortuna, Björn van Sambeek, Evan Appleton, Alex H M Ng, Parastoo Khoshakhlagh, Yuancheng Ryan Lu, James Cameron, Ricardo N Ramirez, Yuting Chen, Chun-Ting Wu, Jeremy Y Huang, Yuqi…
Lamellar Schwann cells in the Pacinian corpuscle potentiate vibration perception
Source: Science advances Authors: Yuh-Tarng Chen, Dominica de Thomas Wagner, Alastair J Loutit, Ali Nourizonoz, Marina Ulanova, Danai Graikou, Man-Shan Chang, Mary-Claude Croisier-Coeytaux, Stéphanie Clerc-Rosset, Jérôme Blanc, Graham Knott, Kuo-Sheng Lee, Daniel Huber, Publication Date: Wed, 11 Jun 2025 06:00:00 -0400 Sci Adv. 2025 Jun…
Factors associated with efficacy of occipital nerve stimulation in medically intractable chronic cluster headache
Source: Headache Authors: Roemer B Brandt, Casper S Lansbergen, Linda Kollenburg, Michel D Ferrari, Frank J P M Huygen, Cecile C de Vos, Rolf Fronczek, Occipital Nerve Stimulation in Medically Intractable Chronic Cluster Headache (ICON) trial study group, Publication Date: Wed, 11 Jun 2025 06:00:00…
Neural determinants of the increase in muscle strength and force steadiness of the untrained limb following a 4 week unilateral training
Source: The Journal of physiology Authors: E Lecce, P Amoruso, A Del Vecchio, A Casolo, F Felici, D Farina, I Bazzucchi, Publication Date: Thu, 12 Jun 2025 06:00:00 -0400 J Physiol. 2025 Jun 11. doi: 10.1113/JP288954. Online ahead of print. ABSTRACT Enhanced untrained muscle strength…
Can we study whisker movements to gain insights into the natural sensory behaviours of mammals?
Source: The Journal of physiology Authors: Robyn A Grant, Publication Date: Thu, 12 Jun 2025 06:00:00 -0400 J Physiol. 2025 Jun 12. doi: 10.1113/JP288053. Online ahead of print. ABSTRACT Neuroscientists, behavioural scientists, mechanical engineers and roboticists collaborate in the broad field of whisker science to…
Dispersed components drive temperature sensing and response in plants
Source: Science (New York, N.Y.) Authors: Avilash Singh Yadav, Sridevi Sureshkumar, Alok Krishna Sinha, Sureshkumar Balasubramanian, Publication Date: Thu, 12 Jun 2025 06:00:00 -0400 Science. 2025 Jun 12;388(6752):1161-1166. doi: 10.1126/science.adv5407. Epub 2025 Jun 12. ABSTRACT Plants are highly sensitive to temperature, and climate change is…