June 12-18, 2026
Showing 1-25 of 73.
Parabrachial Ntsr1 neurons modulate food intake and anxiety through a projection to the ventromedial hypothalamus
Source: Proceedings of the National Academy of Sciences of the United States of America Authors: Jordan L Pauli, Sekun Park, Rachel R Felix, Richard D Palmiter, Publication Date: Wed, 22 Jul 2026 06:00:00 -0400 Proc Natl Acad Sci U S A. 2026 Jul 28;123(30):e2605466123. doi:…
A cortical-subcortical circuit underlies pain sensitization driven by sleep deprivation
Source: Cell reports Authors: Ruizhen Huang, Yuting Wang, Boyu Jiao, Yue Huang, Yanhan Wu, Lan Cao, Shijuan Qiu, Yangdi Luo, Biyao Lin, Tao Luo, Bin Jiang, Wenya Pei, Junting Huang, Publication Date: Mon, 20 Jul 2026 06:00:00 -0400 Cell Rep. 2026 Jul 20;45(7):117693. doi: 10.1016/j.celrep.2026.117693….
Therapeutic Effects of Spent Ground Coffee Oil on Nociception, Anxiety- and Depression-Like Behaviors, and Inflammatory Mechanisms in a CFA-Induced Intraplantar Inflammation Model in Mice
Source: Molecular neurobiology Authors: Elisa Mitkus Flores Lins, Anelise Leal Vieira Cubas, Bruna Hoffmann de Oliveira, Eduarda Behenck Medeiros, Khiany Mathias, Scheila Iria Kraus, Daniel Fernandes Martins, Josiel Mileno Mack, Anna Paula Piovezan, Fabricia Petronilho, Josiane Budni, Franciane Bobinski, Publication Date: Wed, 22 Jul 2026…
Spinal cord regeneration deploys cell-type specific developmental and non-developmental strategies to restore neuron diversity
Source: Nature communications Authors: Avery Angell Swearer, Samuel B Perkowski, Iba Husain, Thiago A Figueiredo, Morgan E McCartney, Andrea E Wills, Publication Date: Mon, 20 Jul 2026 06:00:00 -0400 Nat Commun. 2026 Jul 20. doi: 10.1038/s41467-026-75273-5. Online ahead of print. ABSTRACT A major goal of…
Structural and functional basis of antinociceptive action of χ-conotoxin AoIA at the noradrenaline transporter
Source: Nature structural & molecular biology Authors: Oliver J V Belleza, Heng Zhang, Helmut Schmidhammer, Tye I Gonzalez, Cosmin I Ciotu, Nataša Tomašević, Carlo Martin M Ocampo, Jomari C Fernando, Johannes Koehbach, Paula Schwarz, Mounaf Al Makhlouf, Gabor Tajti, Simon Hasinger, Nina Kastner, Orcun Avsar,…
Macrophage migration inhibitory factor (MIF) antagonist ISO-1 reduces neuroinflammation and neuropathic pain in a sex-dependent manner
Source: Pain Authors: Monica Pontearso, Anirban Bhattacharyya, Pavel Adamek, Daniel Vasconcelos, Jakub Slepicka, Mario Heles, Diana Spicarova, Jiri Palecek, Publication Date: Mon, 20 Jul 2026 06:00:00 -0400 Pain. 2026 Jul 21. doi: 10.1097/j.pain.0000000000004066. Online ahead of print. ABSTRACT Peripheral neuropathy is a global health concern…
A sync state in the midbrain dopamine network for interoceptive nutrient learning
Source: Neuron Authors: Xiao Yang, Weijie Yan, Weixuan Lu, Ruijie Wang, Dingning Li, Zhichao Wang, Huaxing Han, Xianfei Yang, Mengdie Yang, Xiao Han, Rui Song, Yao Lu, Guang Chen, Rong Gong, Publication Date: Wed, 22 Jul 2026 06:00:00 -0400 Neuron. 2026 Jul 22:S0896-6273(26)00531-3. doi: 10.1016/j.neuron.2026.07.002….
A Time-Efficient and Reproducible Rat Model of Myofascial Pain Syndrome-Like Phenotypes Induced by Repeated Mechanical Impact and Eccentric Exercise
Source: Journal of pain research Authors: Zixu Lv, Wenlong Yang, Yingying Liu, Fangming Liu, Miaomiao Tang, Xueqi Li, Guanxi Jiang, Linlin Wang, Zike Dong, Publication Date: Wed, 22 Jul 2026 06:00:00 -0400 J Pain Res. 2026 Jul 17;19:601716. doi: 10.2147/JPR.S601716. eCollection 2026. ABSTRACT BACKGROUND: Existing…
The cannabinoid receptor 1 suppresses neuropeptide Y transcription in the peripheral nervous system to mediate analgesia
Source: The Journal of biological chemistry Authors: YongMin Liu, Xue Gong, Yindi Wang, Zongqi Huang, Jiayi Li, KeXing Wan, Wen Liu, Li Kou, Fangfang Bi, Man Li, Publication Date: Tue, 21 Jul 2026 06:00:00 -0400 J Biol Chem. 2026 Jul 21:113350. doi: 10.1016/j.jbc.2026.113350. Online ahead…
Late-pregnancy oxytocin alleviates neuroinflammation and hyperalgesia in chronic migraine model via PVN to NTS oxytocinergic projections and ECM-receptor interaction signaling
Source: Brain, behavior, and immunity Authors: Lintao Wang, Ziming Zeng, Yanjie Zhou, Chuanqi Gu, Yu Zhang, Liu Yang, Wanbin Huang, Shikuan Ding, Xiaoping Miao, Zheman Xiao, Publication Date: Sun, 19 Jul 2026 06:00:00 -0400 Brain Behav Immun. 2026 Jul 19;138:106919. doi: 10.1016/j.bbi.2026.106919. Online ahead of…
Misregulation of T-box transcription factors drives BNP-NPR1 signalling underlying chronic itch
Source: Nature communications Authors: Xiaolong Dai, Michael Kitching, Wenke Cheng, Rengang Luo, Lianlian Li, Renkai Zhu, Chunxu Shan, Weiwei Chen, Timo Buhl, Andrea Szegedi, Jorg Buddenkotte, Shouming Xu, Jiafu Wang, Jianghui Meng, Publication Date: Fri, 17 Jul 2026 06:00:00 -0400 Nat Commun. 2026 Jul 17….
Peripheral regeneration of Aβ low-threshold mechanoreceptors is limited despite activation of regenerative transcriptional pathways
Source: The Journal of physiology Authors: Sara Bolívar, Natàlia Martínez-Mateu, David Ovelleiro, Esther Udina, Publication Date: Fri, 17 Jul 2026 06:00:00 -0400 J Physiol. 2026 Jul 17. doi: 10.1113/JP291211. Online ahead of print. ABSTRACT Peripheral neurons can regenerate after nerve injury, yet functional recovery is…
Proprioceptive cortical neurons implement optimal state estimation
Source: Current biology : CB Authors: Mélanie Palacio-Manzano, Irina Scheer, Mario Prsa, Publication Date: Tue, 07 Jul 2026 06:00:00 -0400 Curr Biol. 2026 Jul 20;36(14):3623-3635.e6. doi: 10.1016/j.cub.2026.06.027. Epub 2026 Jul 7. ABSTRACT While the primary somatosensory cortex (S1) is known to be essential for skilled…
Quantifying Changes in Pain Sensitivity Using Reproducible Transcutaneous Optogenetic Stimulation in Behaving Mice
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience Authors: Yu-Feng Xie, Christopher Dedek, Steven A Prescott, Publication Date: Tue, 23 Jun 2026 06:00:00 -0400 J Neurosci. 2026 Jul 22;46(29):e0277262026. doi: 10.1523/JNEUROSCI.0277-26.2026. ABSTRACT Optogenetics provides an unprecedented opportunity to delineate…
Catecholamine-mediated release of miR-133a-3p from adipocytes regulates the onset of chronic primary pain
Source: The Journal of clinical investigation Authors: Nathaniel P Hernandez, Jiegen Chen, Yiling Qian, Xin Zhang, Yaomin Wang, Brittney P Ciszek, Xianglong Gao, Marguerita E Klein, Yun-Ling Pai, Mohamad Karaky, Carolina B Meloto, Francesca Montagna, Matt Kanke, Clair Crewe, Luda Diatchenko, Praveen Sethupathy, Andrea G…
Genetic regulation of cell type-specific chromatin accessibility contributes to migraine etiology
Source: The journal of headache and pain Authors: Qiuhan Xu, Zhaohui Chai, Yuning Zhang, Jian Shen, Publication Date: Tue, 21 Jul 2026 06:00:00 -0400 J Headache Pain. 2026 Jul 21. doi: 10.1186/s10194-026-02450-8. Online ahead of print. ABSTRACT BACKGROUND: Migraine is a common and disabling neurological…
Stress-induced analgesia via supraspinal gate control
Authors Zhang Y, Ma Q Source Neuron, 114, 2078-2080 In this issue of Neuron, Haenraets et al. identify spinal GABAergic interneurons necessary for stress-induced analgesia.1 They receive tonic inhibitory inputs from the rostral ventromedial medulla, and their disinhibition by stress establishes a spinal gate control of pain….
Effects of Metabolic Dysregulation on Macrophage Polarization in Rheumatoid Arthritis
Source: Arthritis & rheumatology (Hoboken, N.J.) Authors: Xinyue Zhang, Xiaoyue Deng, Shixiong Wei, Mengtao Li, Xiaofeng Zeng, Publication Date: Thu, 18 Jun 2026 06:00:00 -0400 Arthritis Rheumatol. 2026 Jun 18. doi: 10.1002/art.70253. Online ahead of print. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease…
Interictal serum L-kynurenine and PACAP-38 levels in relation to allodynia and migraine subtypes
Source: Headache Authors: Enes Durak, Aslı Aksoy Gündoğdu, Savaş Güzel, Ahsen Yılmaz, Publication Date: Thu, 18 Jun 2026 06:00:00 -0400 Headache. 2026 Jun 18. doi: 10.1111/head.70143. Online ahead of print. ABSTRACT OBJECTIVE: This study aimed to evaluate the relationship between serum levels of L-kynurenine (L-KYN)…
Effects of Topical Lidocaine and Benzocaine on Pain Level and Injection Satisfaction in Arteriovenous Fistula Catheter Applications
Source: Pain management nursing : official journal of the American Society of Pain Management Nurses Authors: Sevil Güler, Ali Kaplan, Seda Şahan, Murat Hayri Sipahioğlu, Publication Date: Wed, 17 Jun 2026 06:00:00 -0400 Pain Manag Nurs. 2026 Jun 17:S1524-9042(26)00188-8. doi: 10.1016/j.pmn.2026.05.016. Online ahead of print….
Effect of the active cycle breathing technique on pain, anxiety and arterial blood oxygen saturation in patients undergoing coronary artery bypass grafting
Source: BMC anesthesiology Authors: Morteza Solati Kooshkqazi, Mahnaz Rakhshan, Hojatollah Roosta, Fatemeh Shirazi, Publication Date: Thu, 18 Jun 2026 06:00:00 -0400 BMC Anesthesiol. 2026 Jun 17. doi: 10.1186/s12871-026-03953-2. Online ahead of print. ABSTRACT PURPOSE: Addressing pain and anxiety after coronary artery bypass grafting (CABG) is…
Long-term safety and continued clinical benefit of erenumab 70 mg in Asian patients with chronic migraine: an open-label extension of the phase 3 DRAGON study
Source: The journal of headache and pain Authors: Shengyuan Yu, Byung-Kun Kim, Hebo Wang, Jiying Zhou, Partha Banerjee, Jeremie Lincy, Evgeniya Reshetnyak, Zheng Li, Denise Leclair, Shuu-Jiun Wang, Publication Date: Thu, 18 Jun 2026 06:00:00 -0400 J Headache Pain. 2026 Jun 17. doi: 10.1186/s10194-026-02406-y. Online…
Effects of external oblique intercostal plane block on postoperative pain and analgesic requirement in laparoscopic cholecystectomy: a prospective randomized controlled trial
Source: BMC anesthesiology Authors: Mazlum Dursun, Hülya Tosun Söner, Selen Topalel, Meral Erdal Erbatur, Osman Uzundere, Sedat Kaya, Erhan Gökçek, Publication Date: Thu, 18 Jun 2026 06:00:00 -0400 BMC Anesthesiol. 2026 Jun 17. doi: 10.1186/s12871-026-04029-x. Online ahead of print. ABSTRACT BACKGROUND: Laparoscopic cholecystectomy (LC) is…
Characterising injury-related perceived threat trajectories after acute, isolated extremity injuries: A prospective cohort study
Source: The journal of pain Authors: Prudence Butler, Nigel Armfield, Shaun O’Leary, Gerrit van de Pol, Melita J Giummarra, Michele Sterling, Publication Date: Wed, 17 Jun 2026 06:00:00 -0400 J Pain. 2026 Jun 17:106363. doi: 10.1016/j.jpain.2026.106363. Online ahead of print. ABSTRACT ‘Perceived threat’, or the…
Comparison of intrathecal morphine versus thoracic paravertebral block for video-assisted thoracoscopic surgery: a randomized non-inferiority trial
Source: Regional anesthesia and pain medicine Authors: Cengiz Kaya, Kubranur Demirkol, Elif Bengi Sener, Ismail Serhat Kocamanoglu, Hesham Elsharkawy, Publication Date: Wed, 17 Jun 2026 06:00:00 -0400 Reg Anesth Pain Med. 2026 Jun 17:rapm-2026-107927. doi: 10.1136/rapm-2026-107927. Online ahead of print. ABSTRACT BACKGROUND: Although widely performed,…