July 13-19, 2024
Showing 1-25 of 105.
STING recognition of viral dsDNA by nociceptors mediates pain in mice.
Source: Brain Behav Immun 2024 Jul 16;. doi: 10.1016/j.bbi.2024.07.013 Authors: Lee SH, Bonifacio F, Prudente AS, Choi Y, Roh J, Adjafre BL, Park CK, Jung SJ, Cunha TM, Berta T Pain is often one of the initial indicators of a viral infection, yet our understanding…
Efficacy of a Pain Self-Management Intervention Tailored to People With HIV: A Randomized Clinical Trial.
July 13-19, 2024 | |
Source: JAMA Intern Med 2024 Jul 15; . doi: 10.1001/jamainternmed.2024.3071Authors: Jones KF, Long DM, Bair MJ, Agil D, Browne L, Burkholder G, Clay OJ, Conder K, Durr AL, Farel CE, King K, Johnson B, Liebschutz JM, Demonte W, Leone M, Mullen L, Orris SM, Thomas…
Peptide and Peptidomimetic Inhibitors Targeting the Interaction of Collapsin Response Mediator Protein 2 with the N-Type Calcium Channel for Pain Relief.
July 13-19, 2024 | |
Source: ACS Pharmacol Transl Sci 2024 Jul 12; 7(7). doi: 10.1021/acsptsci.4c00181Authors: Perez-Miller S, Gomez K, Khanna R Ion channels serve pleiotropic functions. Often found in complexes, their activities and functions are sculpted by auxiliary proteins. We discovered that collapsin response mediator protein 2 (CRMP2) is…
Nitric Oxide Donor Sodium Nitroprusside Reduces Racemic Ketamine-But Not Esketamine-Induced Pain Relief.
July 13-19, 2024 | |
Source: ACS Pharmacol Transl Sci 2024 Jul 12; 7(7). doi: 10.1021/acsptsci.4c00133Authors: Dahan A, Jansen S, van der Schrier R, Sarton E, Dadiomov D, van Velzen M, Olofsen E, Niesters M The anesthetic, analgesic and antidepressant drug ketamine produces dissociation with symptoms of psychosis and anxiety,…
The role of microRNAs in atopic dermatitis.
July 13-19, 2024 | |
Source: Noncoding RNA Res 2024 Dec; 9(4). doi: 10.1016/j.ncrna.2024.05.012Authors: Khosrojerdi M, Azad FJ, Yadegari Y, Ahanchian H, Azimian A Atopic dermatitis (AD), known as eczema, is a chronic inflammatory skin condition affecting millions worldwide. This abstract provides an overview of the clinical features and underlying…
Interictal widespread pressure hyperalgesia and aura: associations with vestibular migraine in a cross-sectional study.
July 13-19, 2024 | |
Source: Front Neurol 2024; 15. doi: 10.3389/fneur.2024.1405590Authors: Toriyama T, Hanaoka Y, Horiuchi T Patients with vestibular migraine (VM) exhibit higher levels of central sensitization and share similar disorder characteristics with migraine with vestibular symptoms (MwVS), except in terms of disability. These patients experience fluctuating mechanical…
Beyond Chronic Pain Exploring Body-Brain Interaction to Understand and Treat Chronic Pain Conditions.
July 13-19, 2024 | |
Source: Cyberpsychol Behav Soc Netw 2024 Jul; 27(7). doi: 10.1089/Cyber.2024.26824.ceuAuthors: Genovese LA, Riva G, Lernia DD Pubmed ID: https://pubmed.ncbi.nlm.nih.gov/39023291/
Enhancing virtual reality for chronic pain management.
July 13-19, 2024 | |
Source: Pain 2024 Aug 01; 165(8). doi: 10.1097/j.pain.0000000000003295Authors: Yang QH, Lu JY Pubmed ID: https://pubmed.ncbi.nlm.nih.gov/39023337/
Migraine heritability and beyond: A scoping review of twin studies.
July 13-19, 2024 | |
Source: Headache 2024 Jul 18; . doi: 10.1111/head.14789Authors: Olofsson IA This scoping review aimed to summarize current knowledge from twin studies on migraine. Migraine heritability, genetic correlations with migraine comorbid disorders, and the use of discordant twin pairs in migraine research are described. Further, the…
Silencing of FTO inhibits oxidative stress to relieve neuropathic pain by m6A modification of GPR177.
July 13-19, 2024 | |
Source: Immun Inflamm Dis 2024 Jul; 12(7). doi: 10.1002/iid3.1345Authors: Liu L, Liu M, Song Z, Zhang H Neuropathic pain (NP) is a challenging health condition owing to its complex nature and associated multiple etiologies. The occurrence of NP involves the abnormal activity of neurons mediated…
Reduced hepatic impairment study to evaluate pharmacokinetics and safety of zavegepant and to inform dosing recommendation for hepatic impairment.
July 13-19, 2024 | |
Source: Clin Transl Sci 2024 Jul; 17(7). doi: 10.1111/cts.13813Authors: Bhardwaj R, Donohue MK, Madonia J, Morris B, Marbury TC, Matschke KT, Croop R, Bertz R, Liu J Zavegepant, a high-affinity, selective, small-molecule calcitonin gene-related peptide (CGRP) receptor antagonist, is approved in the United States for…
Body composition and body mass index are independently associated with widespread pain and experimental pain sensitivity in older adults: a pilot investigation.
July 13-19, 2024 | |
Source: Front Pain Res (Lausanne) 2024; 5. doi: 10.3389/fpain.2024.1386573Authors: Johnson AJ, Peterson JA, Vincent HK, Manini T, Cruz-Almeida Y Chronic musculoskeletal (MSK) pain is prevalent in older adults and confers significant risk for loss of independence and low quality of life. While obesity is considered…
A thorough investigation into the correlation between migraines and the gut microbiome: an in-depth analysis using Mendelian randomization studies.
July 13-19, 2024 | |
Source: Front Neurol 2024; 15. doi: 10.3389/fneur.2024.1356974Authors: Zang X, Du Y, Jiang M, Zhou S, Wang L, Han X A growing body of evidence underscores a significant association between neurological disorders, particularly migraines, and the gut microbiota. However, a research gap persists in understanding the…
Application of the IASP Grading System to Identify Underlying Pain Mechanisms in Patients with Knee Osteoarthritis: A Prospective Cohort Study.
July 13-19, 2024 | |
Source: Clin J Pain 2024 Jul 17; . doi: 10.1097/AJP.0000000000001234Authors: Vervullens S, Meert L, Meeus M, Heusdens CHW, Verdonk P, Foubert A, Abatih E, Durnez L, Verbrugghe J, Smeets RJEM This study aimed to apply the International Association for the Study of Pain (IASP) grading…
Virtual Reality for Sub-Acute Pain After Orthopedic Traumatic Musculoskeletal Injuries: A Mixed Methods Pilot Study.
July 13-19, 2024 | |
Source: Clin J Pain 2024 Jul 17; . doi: 10.1097/AJP.0000000000001231Authors: Mace RA, Brewer JR, Cohen JE, Ly TV, Weaver MJ, Borsook D Acute orthopedic traumatic musculoskeletal injuries are prevalent, costly, and often lead to persistent pain and functional limitations. Psychological risk factors (pain catastrophizing and…
The Brain-Gut Connection: In inflammatory bowel disease, mental stress can produce two painful types of physical responses.
July 13-19, 2024 | |
Source: Sci Am 2023 Sep 01; 329(2). doi: 10.1038/scientificamerican0923-86Authors: Fischman J, Studios NM Pubmed ID: https://pubmed.ncbi.nlm.nih.gov/39017078/
Short- and medium-term effects of a single session of pain neuroscience education on pain and psychological factors in patients with chronic low back pain. A single-blind randomized clinical trial.
July 13-19, 2024 | |
Source: Eur J Pain 2024 Jul 17; . doi: 10.1002/ejp.4700Authors: Tomás-Rodríguez MI, Asensio-García MDR, García RN, Delicado-Miralles M, Sánchez SH, Segura-Heras JV Biopsychosocial approach in patients suffering chronic low back pain (CLBP) promotes pain self-management strategies. Current evidence recommends high dose of Pain Neuroscience Education…
The role of non-coding RNAs in neuropathic pain.
July 13-19, 2024 | |
Source: Pflugers Arch 2024 Jul 17; . doi: 10.1007/s00424-024-02989-yAuthors: He X, Yang H, Zheng Y, Zhao X, Wang T Neuropathic pain (NPP) is a refractory pain syndrome, caused by damage or disease of the somatosensory nervous system and characterized by spontaneous pain, hyperalgesia, abnormal pain…
Intradiscal Autologous Biologics for the Treatment of Chronic Discogenic Low Back Pain.
July 13-19, 2024 | |
Source: Curr Pain Headache Rep 2024 Jul 17; . doi: 10.1007/s11916-024-01294-8Authors: Ufondu W, Robinson CL, Hussain N, D’Souza RS, Karri J, Emerick T, Orhurhu VJ PURPOSE OF REVIEW: The purpose of this narrative review is to evaluate the efficacy of the most commonly studied intradiscal biologics…
Hyperactivity of the medial thalamus in patients with photophobia-associated migraine.
July 13-19, 2024 | |
Source: Headache 2024 Jul 18; . doi: 10.1111/head.14785Authors: Suzuki Y, Kiyosawa M, Wakakura M, Ishii K To examine cerebral functional alterations associated with sensory processing in patients with migraine and constant photophobia. Pubmed ID: https://pubmed.ncbi.nlm.nih.gov/39023425/
Dietary supplementation of vitamin B1 prevents the pathogenesis of osteoarthritis.
July 13-19, 2024 | |
Source: Proc Natl Acad Sci U S A 2024 Jul 23; 121(30). doi: 10.1073/pnas.2408160121Authors: Shen S, Liang Y, Zhao Y, Hu Z, Huang Y, Wu Y, Liu Y, Fan S, Wang Q, Xiao P As the primary cause for chronic pain and disability in elderly…
Selective serotonin re-uptake inhibitors affect craniofacial structures in a mouse model.
July 13-19, 2024 | |
Source: PLoS One 2024; 19(7). doi: 10.1371/journal.pone.0307134Authors: Saluan QN, Bauer GR, Vyas H, Mohi A, Durham EL, Cray JJ Selective serotonin re-uptake inhibitors (SSRI) widely used in the treatment of depression, anxiety, obsessive compulsive disorder, fibromyalgia, and migraine are among the most heavily prescribed drug…
How is cognitive behavioural therapy for insomnia delivered to adults with comorbid persistent musculoskeletal pain and disordered sleep? A scoping review.
July 13-19, 2024 | |
Source: PLoS One 2024; 19(7). doi: 10.1371/journal.pone.0305931Authors: Browne A, Cahalan R, O’ Sullivan K Disordered sleep and persistent musculoskeletal pain are highly comorbid. Behavioural interventions such as Cognitive Behavioural Therapy for Insomnia (CBT-I) have shown promise in the management of both disordered sleep and persistent…
Prevalence of neuropathic pain in patients with symptomatic endometriosis: Assessment using the DN4 score.
July 13-19, 2024 | |
Source: Eur J Obstet Gynecol Reprod Biol 2024 Jul 07; 300. doi: 10.1016/j.ejogrb.2024.07.013Authors: Bouko-Levy E, Auditeau E, Marguerite F, Lacorre A, Gauthier T The mechanisms underlying pain in cases of endometriosis or chronic pelvic pain are complex, often involving various types of pain; mainly nociceptive…
The roles of innate immune cells in atopic dermatitis.
July 13-19, 2024 | |
Source: J Innate Immun 2024 Jul 18; . doi: 10.1159/000539534Authors: Pan Y, Wang Y, Xu M, Zhong M, Peng X, Zeng K, Huang X Atopic dermatitis (AD) is a chronic inflammatory skin condition characterized by recurrent eczematous lesions and severe pruritus. The economic burden and…