January 23-29, 2026
Showing 1-25 of 42.
NPD1/GPR37 signaling protects against painful traumatic brain injury and comorbidities by regulating demyelination, glial responses, and neuroinflammation in the mouse brain
Source: Brain, behavior, and immunity Authors: Junli Zhao, Runda Li, Yuqing Wang, Sharat Chandra, Vivian Zhang, Haichen Wang, Ru-Rong Ji, Publication Date: Fri, 12 Dec 2025 06:00:00 -0500 Brain Behav Immun. 2026 Feb;132:106219. doi: 10.1016/j.bbi.2025.106219. Epub 2025 Dec 10. ABSTRACT Traumatic brain injury (TBI) often…
Brain-immune correlates of quality of life in adolescents with chronic musculoskeletal pain
Source: Brain, behavior, and immunity Authors: Saül Pascual-Diaz, Maria Suñol, Marie-Eve Hoeppli, Emma Biggs, Christopher D King, Nima Aghaeepour, Martin S Angst, Edward Ganio, Amelie Cambriel, Dorien Feyaerts, Brice Gaudilliere, Jennifer N Stinson, Massieh Moayedi, Robert C Coghill, Laura E Simons, Marina López-Solà, Publication Date:…
Activation of Wnt3a Signaling Rescues the Analgesic Efficacy of Morphine by Regulating Microglial Reactivation in the Spinal Cord
Source: Glia Authors: Cheng Li, Hongyu Yao, Mingzheng Wu, Yiran Zhao, Bo Peng, Hong Gao, Donglin Xiong, Xue-Jun Song, Publication Date: Sat, 13 Dec 2025 06:00:00 -0500 Glia. 2026 Feb;74(2):e70122. doi: 10.1002/glia.70122. ABSTRACT Repetitive opioid treatment promotes analgesic tolerance through mechanisms involving opioid-induced neuroinflammation. Here,…
Purinergic Receptor- and Metabotropic Glutamate Receptor 5-Mediated Interactions Between Satellite Glial Cells and Neurons in Rat Trigeminal Ganglia
Source: Glia Authors: Asako Kubo, Koichi Iwata, Masamichi Shinoda, Hirotaka Shinozuka, Toru Taguchi, Kazue Mizumura, Publication Date: Tue, 16 Dec 2025 06:00:00 -0500 Glia. 2026 Feb;74(2):e70126. doi: 10.1002/glia.70126. ABSTRACT Activation of satellite glial cells (SGCs) within the dorsal root ganglia and trigeminal ganglia (TG) has…
Hemorphins, atypical endogenous opiate peptides, in sickle cell disease and their association with pain
Source: Pain Authors: Yanqi Tan, Yavnika Kashyap, Eduardo De La Toba, Seth W Croslow, Meghna Gill, Xiao Guo, Giokdjen Ilktach, Erin Davy, Robert Molokie, Zaijie Jim Wang, Jonathan V Sweedler, Publication Date: Fri, 12 Dec 2025 06:00:00 -0500 Pain. 2026 Feb 1;167(2):326-337. doi: 10.1097/j.pain.0000000000003859. Epub…
From skin to spinal Cord: How IL-17a Drives psoriatic chronic itch
Source: Brain, behavior, and immunity Authors: Xin Liu, Jian Jiang, Shiying Lin, Wenqiang Ge, Qingxiao Tao, Suwen Liu, Ouyang Zhanmu, Yang Yang, Bao Chai, Jingyu Zhang, Man Li, Hongxiang Chen, Publication Date: Thu, 11 Dec 2025 06:00:00 -0500 Brain Behav Immun. 2026 Feb;132:106218. doi: 10.1016/j.bbi.2025.106218….
Meteorin Resolves Nociceptive Hypersensitivity by Reducing Connexin-Mediated Coupling in Satellite Glial Cells
Source: Glia Authors: Lone Tjener Pallesen, Anna-Kathrine Pedersen, Ishwarya Sankaranarayanan, Rachel Feldman-Goriachnik, Ole Andreas Ahlgreen, Alana Miranda Pinheiro, Lucy He, Jonas Baake, Mads Würgler Hansen, Mette Richner, Laurits Dall Ellegaard, Kenneth Ahrend Petersen, Lone Fjord-Larsen, Jesper Velgaard Olsen, Gordon Munro, Menachem Hanani, Theodore John Price,…
IL-17A-mediated copper accumulation participates in chronic neuropathic pain-induced cognitive impairment by enhancing microglial synaptic pruning
Source: Brain, behavior, and immunity Authors: Jie Liu, Zheng Li, Xiaoling Peng, Wei Zhao, Tiantian Chu, Jie Ju, Jihao Ren, Feng Gao, Publication Date: Fri, 05 Dec 2025 06:00:00 -0500 Brain Behav Immun. 2026 Feb;132:106208. doi: 10.1016/j.bbi.2025.106208. Epub 2025 Dec 3. ABSTRACT Chronic neuropathic pain…
ELAVL1 Promotes Schwann Cell Oxidative Stress and Ferroptosis in Diabetic Neuropathy via ACSL4 mRNA Stabilization
Source: Glia Authors: Dingwen He, Sikuan Zheng, Xiang Luo, Jiangminghao Zhao, Zhidong Peng, Chongzhi Pan, Xigao Cheng, Publication Date: Wed, 03 Dec 2025 06:00:00 -0500 Glia. 2026 Feb;74(2):e70106. doi: 10.1002/glia.70106. ABSTRACT ELAVL1 is known to regulate mRNA stability in various diseases, but its role in…
New kid on the block: hemorphins in sickle cell disease
Source: Pain Authors: Donovan A Argueta, Kalpna Gupta, Publication Date: Tue, 25 Nov 2025 06:00:00 -0500 Pain. 2026 Feb 1;167(2):249-250. doi: 10.1097/j.pain.0000000000003860. Epub 2025 Nov 13. NO ABSTRACT PMID:41289493 | DOI:10.1097/j.pain.0000000000003860 Pubmed ID: pubmed:41289493 Identifiers: pmid:41289493, doi:10.1097/j.pain.0000000000003860,
Post-traumatic osteoarthritis in aged rodents is associated with brain changes that correlate with joint remodeling
Source: The journal of pain Authors: Jacob L Griffith, Pedro A Valdes-Hernandez, Taylor D Yeater, Shane H Priester, Marcelo Febo, Yenisel Cruz-Almeida, Kyle D Allen, Publication Date: Mon, 24 Nov 2025 06:00:00 -0500 J Pain. 2026 Feb;39:105594. doi: 10.1016/j.jpain.2025.105594. Epub 2025 Nov 22. ABSTRACT Preclinical…
Searching for blood biomarkers and treatment targets in Women with fibromyalgia – Protein interaction patterns and anti-satellite glia cell IgG antibodies as promising candidates
Source: Brain, behavior, and immunity Authors: Karolina Af Ekenstam, Joana Menezes, Jenny E Jakobsson, Helene Silverstein, Emerson Krock, Jeanette Tour, Katalin Sandor, Alexandra Kuliszkiewicz, Matthew Hunt, Kim Kultima, Macarena Tejos-Bravo, Camilla I Svensson, Eva Kosek, Publication Date: Fri, 21 Nov 2025 06:00:00 -0500 Brain Behav…
Distinct multidimensional anger profiles predict current and long-term chronic pain outcomes
Source: The journal of pain Authors: Marine Granjon, Noel Vest, Sean C Mackey, Gadi Gilam, Publication Date: Thu, 20 Nov 2025 06:00:00 -0500 J Pain. 2026 Feb;39:105611. doi: 10.1016/j.jpain.2025.105611. Epub 2025 Nov 19. ABSTRACT Anger is prevalent in chronic pain (CP), often co-occurring with heightened…
Mapping somatosensory afferent circuitry to bone identifies neurotrophic signals required for fracture healing
Source: Science (New York, N.Y.) Authors: Mingxin Xu, Zhao Li, Neelima Thottappillil, Masnsen Cherief, Manyu Zhu, Xin Xing, Mario Gomez-Salazar, Chunbao Rao, Sowmya Ramesh, Juliet M Mwirigi, Ishwarya Sankaranarayanan, Diana Tavares-Ferreira, Chi Zhang, Xue-Wei Wang, Mary Archer, Yun Guan, Robert J Tower, Patrick Cahan, Theodore…
Long-Term Effectiveness and Persistence Factors of Anti-CGRP Monoclonal Antibodies in Migraine: 2-Year Results From the EUREkA Cohort
Source: Neurology Authors: Edoardo Caronna, Rut Mas-de-Les-Valls, Gabriella Egeo, Manuel Millán Vázquez, Candela Nieves-Castellanos, Leonardo Portocarrero-Sánchez, Gloria Vaghi, Joana Rodríguez-Montolio, as the European Real-World Study on the Use of Anti-CGRP Monoclonal Antibodies in Migraine (EUREkA) Study Group, Alex Jaimes, Albert Muñoz-Vendrell, Renato Oliveira, Marcos Polanco,…
Targeting glial-orchestrated neuroinflammation in migraine pathophysiology
Source: The journal of headache and pain Authors: Weiwei Lu, Yuan Zhang, Chen Shi, Yu Tao, Shaoxin Li, Yufang Sun, Fuhai Ji, Gang Chen, Terrance P Snutch, Jin Tao, Publication Date: Thu, 29 Jan 2026 06:00:00 -0500 J Headache Pain. 2026 Jan 28. doi: 10.1186/s10194-026-02272-8….
Intra-articular glucocorticoid injections for knee osteoarthritis
Source: CMAJ : Canadian Medical Association journal = journal de l’Association medicale canadienne Authors: Joy Du, Gillian Hawker, Lauren K King, Publication Date: Mon, 26 Jan 2026 06:00:00 -0500 CMAJ. 2026 Jan 25;198(3):E88. doi: 10.1503/cmaj.250719. NO ABSTRACT PMID:41587804 | DOI:10.1503/cmaj.250719 Pubmed ID: pubmed:41587804 Identifiers: pmid:41587804,…
Integrating Primary Care Nurses in Chronic Pain Management: Barriers, Opportunities, and Insights from a Qualitative Focus Group Study
Source: Pain management nursing : official journal of the American Society of Pain Management Nurses Authors: Andréanne Bernier, Anaïs Lacasse, Marie-Dominique Poirier, Sylvie Beaudoin, Marie-Eve Poitras, Publication Date: Sun, 25 Jan 2026 06:00:00 -0500 Pain Manag Nurs. 2026 Jan 24:S1524-9042(25)00374-1. doi: 10.1016/j.pmn.2025.12.019. Online ahead of…
Osteoarthritis year in review 2025: Biomechanics
Source: Osteoarthritis and cartilage Authors: Jenna M Qualter, Alexandra N Chertok, Amy Buhler, Elise K Laende, Kerry E Costello, Publication Date: Sun, 25 Jan 2026 06:00:00 -0500 Osteoarthritis Cartilage. 2026 Jan 23:S1063-4584(26)00004-X. doi: 10.1016/j.joca.2026.01.003. Online ahead of print. ABSTRACT OBJECTIVE: Biomechanical loading is a known…
Comparative Effectiveness and Safety of Varying Corticosteroid Doses for Lumbar Epidural Steroid Injections: A Systematic Review and Narrative Synthesis
Source: Pain medicine (Malden, Mass.) Authors: Hoa Ngan Doan, Mathieu Boudier-Revéret, Min Cheol Chang, Publication Date: Sun, 25 Jan 2026 06:00:00 -0500 Pain Med. 2026 Jan 25:pnag016. doi: 10.1093/pm/pnag016. Online ahead of print. ABSTRACT OBJECTIVE: Lumbar epidural steroid injections (ESIs) are widely used to treat…
Oblique subcostal transversus abdominis plane block versus transmuscular quadratus lumborum block for postoperative analgesia and quality of recovery in laparoscopic gynecological surgery: a prospective randomized controlled double-blind trial
Source: BMC anesthesiology Authors: Kübra Cebeci, Selcan Akesen, Seda Cansabuncu, Alp Gurbet, Gürkan Uncu, Publication Date: Sat, 24 Jan 2026 06:00:00 -0500 BMC Anesthesiol. 2026 Jan 24. doi: 10.1186/s12871-026-03643-z. Online ahead of print. NO ABSTRACT PMID:41580664 | DOI:10.1186/s12871-026-03643-z Pubmed ID: pubmed:41580664 Identifiers: pmid:41580664, doi:10.1186/s12871-026-03643-z,
Closed-loop Spinal Cord Stimulation for Chronic Pain: A Systematic Review and Meta-Analysis
Source: Neuromodulation : journal of the International Neuromodulation Society Authors: Luciano Falcão, Gabriel Arruda, Abhishek Goyal, Rafael Andrade Sampaio Silva, Kenzo Ogasawara Donato, Maria Clara Nery Cardoso, Theo Cardoso Ribeiro, André Nishizima, Adil Ahmed, Anderson Matheus Pereira da Silva, Ocilio Ribeiro Gonçalves, Bernardo Assumpção de…
Treating-to-target: remission and low disease activity in systemic lupus erythematosus versus rheumatoid arthritis
Source: Rheumatology (Oxford, England) Authors: Konrad Hüther, Nicolai Leuchten, Martin Aringer, Publication Date: Sat, 24 Jan 2026 06:00:00 -0500 Rheumatology (Oxford). 2026 Jan 24:keag045. doi: 10.1093/rheumatology/keag045. Online ahead of print. ABSTRACT OBJECTIVES: To compare the proportion of patients in remission and low disease activity (LDA)…
Clinical and molecular data to predict flares in DMARD optimization in rheumatoid arthritis: a randomised, controlled, open-label, non-inferiority trial
Source: Rheumatology (Oxford, England) Authors: Francisco J Blanco, Laura Galindo, Belen Acasuso, Vanesa Balboa-Barreiro, Juan D Cañete, Benjamin Fernández-Gutiérrez, Isidoro González-Álvaro, José Luis Pablos Álvarez, Carmen Bejerano-Herrería, Maite Silva-Díaz, Ignacio Rego-Perez, Lucia Lourido, Cristina Ruiz-Romero, Miren Uriarte-Ecenarro, Rosario García-Vicuña, Andrea Cuervo, Julio Ramírez, Raquel Celis,…
Exploring the effects of GLP-1 receptor agonists in fibromyalgia: a propensity-matched real-world cohort using TriNetX research platform
Source: Rheumatology (Oxford, England) Authors: Nouran Eshak, Anushka Irani, Megan Sullivan, Publication Date: Sat, 24 Jan 2026 06:00:00 -0500 Rheumatology (Oxford). 2026 Jan 24:keag033. doi: 10.1093/rheumatology/keag033. Online ahead of print. ABSTRACT OBJECTIVES: We aimed to evaluate the effects of GLP-1 receptor agonists (GLP-1RA) on symptom…