December 5-11, 2025
Showing 1-25 of 32.
Transformer-based deep learning enhances discovery in migraine GWAS
Source: Nature communications Authors: Ziang Meng, Yingchao Song, Yue Jiang, Xianjin Wang, Yang Zou, Xingyuan Li, Hakon Hakonarson, Xiao Chang, Publication Date: Wed, 10 Dec 2025 06:00:00 -0500 Nat Commun. 2025 Dec 10;16(1):11023. doi: 10.1038/s41467-025-65991-7. ABSTRACT Migraine is a complex neurological disorder with substantial heritability,…
Domain-general neural effects of associative learning and expectations on pain and hedonic taste perception
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience Authors: Yili Zhao, In-Seon Lee, Margaret Rose-McCandlish, Qingbao Yu, Dominik Mischkowski, Jason Avery, John E Ingeholm, Richard Reynolds, Gang Chen, Lauren Atlas, Publication Date: Wed, 10 Dec 2025 06:00:00 -0500 J…
Nociceptive sensory neuron-derived NGF orchestrates a fibrotic mesenchymal stromal cell neurogenic niche to drive tendon pathological fibrosis
Source: Nature communications Authors: Yanhao Li, Sa Pang, Xinshu Zhang, Mingkuan Lu, Junjie Zhao, Rongpu Wu, Jiacheng Hu, Jia Jiang, Huajiang Chen, Zemin Ling, Jun Qin, Bo Hu, Shen Liu, Publication Date: Tue, 09 Dec 2025 06:00:00 -0500 Nat Commun. 2025 Dec 10. doi: 10.1038/s41467-025-67396-y….
Galectin-related protein, a key contributor, drives diabetes-associated neuropathic pain
Source: Proceedings of the National Academy of Sciences of the United States of America Authors: Danyang Chen, Jing Wang, Xiang-Jie Song, Zi-Jiao Ding, Qianqian Lou, Yuan-Yuan Chen, Meng-Yuan Wang, Xin-Lu Yang, Zhi Zhang, Juan Li, Wei Wang, Haitao Wang, Publication Date: Mon, 08 Dec 2025…
Harnessing theta-gamma coupled brainwaves using ultrasound for spinal astrocyte revitalization and sustained neuropathic pain relief in mice
Source: Nature communications Authors: Tien Thuy Phan, Sangyep Shin, Ho Jeong Kim, Keunhyung Lee, Tai-Young Kim, Jae-Hun Lee, Dong-Wook Kang, Hyunjin Shin, Hye Eun Lee, Nishani Jayanika Jayathilake, Minseok Koo, Hyungju Park, Hyun-Woo Kim, Yee Joon Kim, Ji Young Mun, Jinhyoung Park, Kyu Pil Lee,…
Characterization and evaluation of an institutional neuraxial antithrombotic clinical decision support tool
Source: Regional anesthesia and pain medicine Authors: Anastasia Borodai, Jeffrey J McKenzie, Bryant Winston Tran, Publication Date: Tue, 06 Aug 2024 06:00:00 -0400 Reg Anesth Pain Med. 2025 Dec 5;50(12):985-987. doi: 10.1136/rapm-2024-105792. NO ABSTRACT PMID:39106988 | DOI:10.1136/rapm-2024-105792 Pubmed ID: pubmed:39106988 Identifiers: pmid:39106988, doi:10.1136/rapm-2024-105792,
Non-inferiority study assessing the utility of postcervical and lumbar radiofrequency ablation steroid use
Source: Regional anesthesia and pain medicine Authors: Mark R Williams, Annie Philip, Soun Sheen, Saumya Aujla, Changyong Feng, Shan Gao, Sarah Kralovic, Joseph Poli, Tammy Ortiz, Tatsiana Stefanos, Janet Pennella-Vaughan, Jennifer S Gewandter, Publication Date: Sat, 03 Aug 2024 06:00:00 -0400 Reg Anesth Pain Med….
Long-term explantation risk in patients with chronic pain treated with spinal cord or dorsal root ganglion stimulation
Source: Regional anesthesia and pain medicine Authors: Kliment Gatzinsky, Beatrice Brink, Kristin Lilja Eyglóardóttir, Tobias Hallén, Publication Date: Wed, 31 Jul 2024 06:00:00 -0400 Reg Anesth Pain Med. 2025 Dec 5;50(12):923-929. doi: 10.1136/rapm-2024-105719. ABSTRACT OBJECTIVE: To investigate long-term explantation risks and causes for the explantation…
Treatment of abdominal migraine in an 8-year-old child with calcitonin gene-related peptide receptor antagonist: A case report
Source: Headache Authors: Yunzhu Tang, Chunyan Lu, Yao Zhou, Shuxia Qian, Publication Date: Wed, 10 Dec 2025 06:00:00 -0500 Headache. 2025 Dec 10. doi: 10.1111/head.70017. Online ahead of print. NO ABSTRACT PMID:41367235 | DOI:10.1111/head.70017 Pubmed ID: pubmed:41367235 Identifiers: pmid:41367235, doi:10.1111/head.70017,
A phase 4, 24-week, open-label study to evaluate the safety and tolerability of once-daily dosing of 75 mg rimegepant for episodic migraine prevention
Source: The journal of headache and pain Authors: Jeremias Antinew, Robert J Fountaine, Vittorio Loprinzo, Esther Straghan, Sergey Dubrovin, Patrizia DeBesi, Nick Vatakis, Terence Fullerton, Publication Date: Tue, 09 Dec 2025 06:00:00 -0500 J Headache Pain. 2025 Dec 9. doi: 10.1186/s10194-025-02225-7. Online ahead of print….
Anesthesia Type during Cancer Surgery: Results of the GA-CARES Randomized, Multicenter Trial
Source: Anesthesiology Authors: Elliott Bennett-Guerrero, Jamie L Romeiser, Samuel DeMaria, Jacob W Nadler, Timothy D Quinn, Sanjeev K Ponnappan, Ryan Wang, Marjorie S Gloff, Kathleen J Lee, Matthew A Levin, Raymond D Sroka, Samuel L Stanley, Dongliang Wang, Aaron R Sasson, GA-CARES Trial Group, Publication…
2026 American Society of Anesthesiologists Practice Guideline on Perioperative Pain Management Using Local and Regional Analgesia for Cardiothoracic Surgeries, Mastectomy, and Abdominal Surgeries
Source: Anesthesiology Authors: Girish P Joshi, Edward Mariano, Nabil M Elkassabany, Monica Harbell, Rebecca L Johnson, Jinlei Li, Lena Napolitano, Gary Schwartz, Santhanam Suresh, Karla E Wyatt-Thompson, Anne Burns, Madhulika Agarkar, Anne Marbella, Stephanie Ramirez, Nancy Sullivan, Aaron Bloschichak, Stacey Uhl, Karen B Domino, Publication…
Manual therapy with exercise for neck pain
Source: The Cochrane database of systematic reviews Authors: Nejin Chacko, Anita R Gross, Jordan Miller, Pasqualina L Santaguida, Stephen J Burnie, Geoffrey M Gelley, Jean-Philippe Paquin, Mujeeb-Rehman Duranai, Pierre Langevin, Neha Chopra-Tandon, Nga Ting Chak, Jan L Hoving, Pavlos Bobos, Publication Date: Tue, 09 Dec…
Effect of Automated Closed-Loop Ventilation vs Protocolized Conventional Ventilation on Ventilator-Free Days in Critically Ill Adults: A Randomized Clinical Trial
Source: JAMA Authors: Jante S Sinnige, Laura A Buiteman-Kruizinga, Janneke Horn, Frederique Paulus, Marcus J Schultz, Ary Serpa Neto, ACTiVE Investigators and the Protective Ventilation Network, Publication Date: Tue, 09 Dec 2025 06:00:00 -0500 JAMA. 2025 Dec 8:e2524384. doi: 10.1001/jama.2025.24384. Online ahead of print. ABSTRACT…
Time-varying comparative effectiveness of surgical or percutaneous revascularization on patient-centred outcomes
Source: CMAJ : Canadian Medical Association journal = journal de l’Association medicale canadienne Authors: Vikram Fielding-Singh, Christian O’Donnell, Jack H Boyd, Meltem Tuna, Mamas A Mamas, Marc Ruel, Louise Y Sun, Publication Date: Mon, 08 Dec 2025 06:00:00 -0500 CMAJ. 2025 Dec 7;197(42):E1436-E1448. doi: 10.1503/cmaj.250312….
Does spontaneous cartilage thickening occur in osteoarthritic knees? Data from IMI-APPROACH and the OAI
Source: Osteoarthritis and cartilage Authors: C Salzlechner, W Wirth, S C Mastbergen, M Kloppenburg, F J Blanco, I K Haugen, F Berenbaum, M P Jansen, Publication Date: Mon, 08 Dec 2025 06:00:00 -0500 Osteoarthritis Cartilage. 2025 Dec 6:S1063-4584(25)01243-9. doi: 10.1016/j.joca.2025.12.002. Online ahead of print. ABSTRACT…
Expression of melatonin receptors in trigeminal and sphenopalatine ganglia: potential targets for primary headache disorders
Source: The journal of headache and pain Authors: Aida Maddahi, Jacob C A Edvinsson, Lars Edvinsson, Diana N Krause, Publication Date: Wed, 10 Dec 2025 06:00:00 -0500 J Headache Pain. 2025 Dec 9;26(1):284. doi: 10.1186/s10194-025-02215-9. ABSTRACT BACKGROUND: Primary headache disorders such as migraine and cluster…
Observations of Early Structural Changes over 6 Years on Magnetic Resonance Imaging in Knees without Radiographic Osteoarthritis
Source: Osteoarthritis and cartilage Authors: Karin Magnusson, Aleksandra Turkiewicz, Jaanika Paemre, Armaghan Mahmoudian, Martin Englund, Publication Date: Mon, 08 Dec 2025 06:00:00 -0500 Osteoarthritis Cartilage. 2025 Dec 6:S1063-4584(25)01242-7. doi: 10.1016/j.joca.2025.12.003. Online ahead of print. ABSTRACT OBJECTIVE: To describe longitudinal changes of Magnetic Resonance Imaging (MRI)…
Differences in Diagnosis and Treatment Across Racial-Ethnic Groups with Co-Occurring Chronic Pain and Opioid Use Disorder: A Scoping Review
Source: Pain medicine (Malden, Mass.) Authors: Julio C Nunes, Gabriel P A Costa, Mayte A Cerezo-Matias, Melissa C Funaro, Claudia M Campbell, Joao P De Aquino, Publication Date: Mon, 08 Dec 2025 06:00:00 -0500 Pain Med. 2025 Dec 8:pnaf173. doi: 10.1093/pm/pnaf173. Online ahead of print….
Longitudinal changes in patient characteristics as drivers of clinical outcomes in the Early Undifferentiated PolyArthritis (EUPA) cohort
Source: Rheumatology (Oxford, England) Authors: Nathalie Carrier, Javier Marrugo, Misti L Paudel, Sophie Roux, Hugues Allard-Chamard, Artur J de Brum-Fernandes, Patrick Liang, Gilles Boire, Publication Date: Mon, 08 Dec 2025 06:00:00 -0500 Rheumatology (Oxford). 2025 Dec 8:keaf650. doi: 10.1093/rheumatology/keaf650. Online ahead of print. ABSTRACT OBJECTIVE:…
Two epigenetic markers of the fibromyalgia syndrome: A matched case-control study
Source: The journal of pain Authors: Marine Delay, Nicolas Macian, Christian Dualé, Bruno Pereira, Youssef Aissouni, Yannick Lippi, Gisèle Pickering, Publication Date: Sun, 07 Dec 2025 06:00:00 -0500 J Pain. 2025 Dec 5;39:105630. doi: 10.1016/j.jpain.2025.105630. Online ahead of print. ABSTRACT MicroRNAs (miRs) are involved in…
Myofascial Pain with Referral: Role of Nociceptive Drive and Central Pain Mechanisms
Source: The journal of pain Authors: Hosam Zebda, Yoly Gonzalez, Heidi Crow, Richard Ohrbach, Publication Date: Sun, 07 Dec 2025 06:00:00 -0500 J Pain. 2025 Dec 5:105629. doi: 10.1016/j.jpain.2025.105629. Online ahead of print. ABSTRACT Referred pain frequently occurs in musculoskeletal pain disorders. The differential role…
Pain modality shapes empathy: Amplified empathic responses for visceral compared to somatic pain
Source: The journal of pain Authors: Milena Pertz, Thomas Penack, Robert Jan Pawlik, Adriane Icenhour, Sigrid Elsenbruch, Publication Date: Sun, 07 Dec 2025 06:00:00 -0500 J Pain. 2025 Dec 5;39:105631. doi: 10.1016/j.jpain.2025.105631. Online ahead of print. ABSTRACT Visceral pain, an evolutionarily prepared signal of interoceptive…
Sacral Nerve Stimulation and Chronic Bladder Pain: Meta-Analysis
Source: Neuromodulation : journal of the International Neuromodulation Society Authors: Rodwan Husein, Moein Tavakkoli, Sara Ahmadi Abhari, Lawrence Hutchinson, Suraj Shah, Anish Thillainathan, Andrew Baranowski, Publication Date: Sun, 07 Dec 2025 06:00:00 -0500 Neuromodulation. 2025 Dec 6:S1094-7159(25)01103-1. doi: 10.1016/j.neurom.2025.09.318. Online ahead of print. ABSTRACT OBJECTIVES:…
Pharmacoepidemiologic characterization of cannabis use and symptomatology in rheumatology using natural language processing of electronic health record clinic notes
Source: The journal of pain Authors: Titilola Falasinnu, Nathan Le, Yiyu Wang, Aishwarya Alagappan, Andrew Walker, Tricia Park, Jerik Leung, Yashaar Chaichian, Michael Weisman, Martha Kenney, Anushka Irani, Selen Bozkurt, Publication Date: Sun, 07 Dec 2025 06:00:00 -0500 J Pain. 2025 Dec 5;39:105633. doi: 10.1016/j.jpain.2025.105633….