December 20-26, 2025
Showing 1-25 of 68.
Esketamine relieves postoperative depression and pain indicators in patients undergoing laparoscopic total hysterectomy
Source: BMC anesthesiology Authors: Jun Jing, Meng-Ying Zhang, Wei-Hong Yin, Yong-Jie Ji, Li Sun, Rui Qu, Yuan-Hai Li, Publication Date: Sat, 20 Dec 2025 06:00:00 -0500 BMC Anesthesiol. 2025 Dec 20. doi: 10.1186/s12871-025-03570-5. Online ahead of print. ABSTRACT OBJECTIVE: This study aimed to investigate the…
The Effects of Massage and Music Interventions on Postoperative Pain Severity Following Cardiac Surgery: A Systematic Review and Meta-analysis of Randomized Controlled Trials
Source: Pain management nursing : official journal of the American Society of Pain Management Nurses Authors: Sare Aktaş, Meryem Yilmaz, Publication Date: Sun, 21 Dec 2025 06:00:00 -0500 Pain Manag Nurs. 2025 Dec 20:S1524-9042(25)00322-4. doi: 10.1016/j.pmn.2025.11.011. Online ahead of print. ABSTRACT OBJECTIVES: To investigate the…
Chronic Pain Is a Brain Network Disorder
Source: JAMA neurology Authors: Julian C Motzkin, Bin He, Kalpna Gupta, Prasad Shirvalkar, Publication Date: Mon, 22 Dec 2025 06:00:00 -0500 JAMA Neurol. 2025 Dec 22. doi: 10.1001/jamaneurol.2025.5065. Online ahead of print. NO ABSTRACT PMID:41428346 | DOI:10.1001/jamaneurol.2025.5065 Pubmed ID: pubmed:41428346 Identifiers: pmid:41428346, doi:10.1001/jamaneurol.2025.5065,
Prediction of opioid use disorder among patients with chronic non-cancer pain receiving long-term opioid therapy
Source: Pain medicine (Malden, Mass.) Authors: Christal N Davis, Yoonjae Lee, Martin D Cheatle, Publication Date: Mon, 22 Dec 2025 06:00:00 -0500 Pain Med. 2025 Dec 22:pnaf161. doi: 10.1093/pm/pnaf161. Online ahead of print. ABSTRACT OBJECTIVE: Assessing opioid use disorder risk in patients prescribed long-term opioid…
Cannabis-Based Products for Chronic Pain : An Updated Systematic Review
Source: Annals of internal medicine Authors: Roger Chou, Rongwei Fu, Azrah Y Ahmed, Benjamin J Morasco, Publication Date: Mon, 22 Dec 2025 06:00:00 -0500 Ann Intern Med. 2025 Dec 23. doi: 10.7326/ANNALS-25-03152. Online ahead of print. ABSTRACT BACKGROUND: Benefits and harms of cannabinoids for chronic…
Annals Video Summary – Cannabis-Based Products for Chronic Pain
Source: Annals of internal medicine Authors: Publication Date: Mon, 22 Dec 2025 06:00:00 -0500 Ann Intern Med. 2025 Dec 23:e2504735VS. doi: 10.7326/ANNALS-25-04735-VS. Online ahead of print. NO ABSTRACT PMID:41429021 | DOI:10.7326/ANNALS-25-04735-VS Pubmed ID: pubmed:41429021 Identifiers: pmid:41429021, doi:10.7326/ANNALS-25-04735-VS,
Defining the Safety and Efficacy of Cannabis for Chronic Pain: Novel Approaches and Reframing Objectives
Source: Annals of internal medicine Authors: Ziva D Cooper, Publication Date: Mon, 22 Dec 2025 06:00:00 -0500 Ann Intern Med. 2025 Dec 23. doi: 10.7326/ANNALS-25-04734. Online ahead of print. NO ABSTRACT PMID:41429022 | DOI:10.7326/ANNALS-25-04734 Pubmed ID: pubmed:41429022 Identifiers: pmid:41429022, doi:10.7326/ANNALS-25-04734,
An Unsupervised Learning Approach for Multimodal Low Back Pain Stratification
Source: Spine Authors: Narasimharao Kowlagi, Eveliina Heikkala, Simo Saarakkala, Jaro Karppinen, Aleksei Tiulpin, Publication Date: Fri, 12 Dec 2025 06:00:00 -0500 Spine (Phila Pa 1976). 2025 Dec 22. doi: 10.1097/BRS.0000000000005593. Online ahead of print. ABSTRACT STUDY DESIGN: Cross-sectional study. OBJECTIVE: This study proposes a novel…
Plasma Proteomics Identifies TAOK3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target
Source: Arthritis & rheumatology (Hoboken, N.J.) Authors: Pengfei Xin, Wenzhen Li, Xinyu A, Jun Shen, Xiaohui Meng, Yanqin Bian, Haihui Han, Zheng Xiang, Lei Ran, Songtao Sun, Jun Xie, Tao Yue, Qi Zhu, Xiaoming Zhang, Lu Xie, Lianbo Xiao, Publication Date: Mon, 22 Dec 2025…
Schwann cell Lrp1 deletion drives trigeminal neuron sensitization and orofacial pain by modulating mitochondrial function and TRPV1/TRPA1 activity
Source: The journal of headache and pain Authors: Zhiting Gong, Morgan Zhang, Naijiang Liu, Kesava Asam, Stefano Martellucci, Bradley Aouizerat, Wendy Campana, Yi Ye, Publication Date: Mon, 22 Dec 2025 06:00:00 -0500 J Headache Pain. 2025 Dec 22;26(1):290. doi: 10.1186/s10194-025-02250-6. ABSTRACT BACKGROUND: Orofacial pain, affecting…
A mouse model of classical trigeminal neuralgia via intradural compression of the trigeminal nerve
Source: The journal of headache and pain Authors: Mostafa W Abdulrahim, Yanxia Chen, Sumil K Nair, Qian Xu, Yaowu Zhang, Oishika Das, Ryan Gensler, James Feghali, A Karim Ahmed, Christopher M Jackson, Judy Huang, Youssef G Comair, Chetan Bettegowda, Xinzhong Dong, Risheng Xu, Publication Date:…
An interpretable metabolomic-driven machine learning model for early prediction of knee structural osteoarthritis progression
Source: Rheumatology (Oxford, England) Authors: Afshin Jamshidi, Guangju Zhai, Ming Liu, Weidong Zhang, Graeme Jones, Flavia M Cicuttini, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Publication Date: Tue, 23 Dec 2025 06:00:00 -0500 Rheumatology (Oxford). 2025 Dec 22:keaf686. doi: 10.1093/rheumatology/keaf686. Online ahead of print. ABSTRACT OBJECTIVES: Osteoarthritis (OA)…
Long-term outcomes of amputation in patients with complex regional pain syndrome (CRPS): a mixed-methods study
Source: Regional anesthesia and pain medicine Authors: Daniël Pc van der Spek, Julian Ghantous, Tjebbe Hagenaars, Marieke A Paping, Frank Jpm Huygen, Maaike Dirckx, Publication Date: Sun, 17 Aug 2025 06:00:00 -0400 Reg Anesth Pain Med. 2025 Dec 23:rapm-2025-106918. doi: 10.1136/rapm-2025-106918. Online ahead of print….
From trigeminal ganglion to cortex: ATG7 emerges as a key integrator of migraine pathways via multi-omics profiling
Source: The journal of headache and pain Authors: Chengcheng Zhang, Yine Song, Baicheng Cao, Yuancan Pan, Yuhan Liu, Jiangyan Wei, Libin Zheng, Lu Liu, Publication Date: Tue, 23 Dec 2025 06:00:00 -0500 J Headache Pain. 2025 Dec 23;26(1):288. doi: 10.1186/s10194-025-02222-w. ABSTRACT BACKGROUND: Migraine is a…
Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Source: The journal of headache and pain Authors: Hao-Ruei Mei, Bianca Mason, Ya-Yu Hu, Aiswarya Saravanan, Shrivatsa Kulkarni, Myan Lam, Shiva Nematgorgani, Joseph B Lesnak, Michael Burton, Gregory Dussor, Publication Date: Tue, 23 Dec 2025 06:00:00 -0500 J Headache Pain. 2025 Dec 23. doi: 10.1186/s10194-025-02261-3….
Cerebellar neurocan gene expression is a common pathogenic factor of trigeminal neuralgia and depression
Source: The journal of headache and pain Authors: Zhangying Zeng, Jianwei Jiang, Xuemei Wu, Xinyue Liao, Yiqian Wang, Li Zhao, Feng Wang, Shitao Rao, Daoshu Luo, Publication Date: Thu, 25 Dec 2025 06:00:00 -0500 J Headache Pain. 2025 Dec 25. doi: 10.1186/s10194-025-02254-2. Online ahead of…
TNF-induced neuropilin-2 in fibroblast-like synoviocytes exacerbates rheumatoid arthritis
Source: Arthritis & rheumatology (Hoboken, N.J.) Authors: Ke Jin, Jingjing Ran, Yuxin Deng, Zhiyong Miao, Ling Wei, Ying Yang, Min Yang, Tong Li, Haitao Niu, Geng Yin, Qibing Xie, Publication Date: Fri, 26 Dec 2025 06:00:00 -0500 Arthritis Rheumatol. 2025 Dec 26. doi: 10.1002/art.70028. Online…
Engineered Cationic Interleukin-1 Receptor Antagonist Outperforms Anakinra at Joint Retention and Preventing IL-1-induced Cartilage Inflammation
Source: Osteoarthritis and cartilage Authors: Timothy L Boyer, Bill Hakim, Luke Childress, Helna M Baby, Ryan M Porter, Ambika G Bajpayee, Publication Date: Fri, 26 Dec 2025 06:00:00 -0500 Osteoarthritis Cartilage. 2025 Dec 24:S1063-4584(25)01281-6. doi: 10.1016/j.joca.2025.12.018. Online ahead of print. ABSTRACT OBJECTIVE: Even after intra-articular…
Tear fluid calcitonin gene-related peptide (CGRP) is elevated during spontaneous migraine attacks – results from a pilot study
Source: The journal of headache and pain Authors: Katharina Kamm, Annika Brandi-Dohrn, Andreas Straube, Stefanie Förderreuther, Ruth Ruscheweyh, Publication Date: Thu, 25 Dec 2025 06:00:00 -0500 J Headache Pain. 2025 Dec 25. doi: 10.1186/s10194-025-02255-1. Online ahead of print. ABSTRACT BACKGROUND: Calcitonin gene-related peptide (CGRP) plays…
Visual hypersensitivity as a transdiagnostic marker of surgical pain response in arthritis and chronic pain syndromes
Source: Arthritis & rheumatology (Hoboken, N.J.) Authors: Noah Waller, Steven E Harte, Richard E Harris, Andrew Schrepf, Tristin Smith, Eric Ichesco, Chelsea Kaplan, Flavia Sunzini, Deeba Minhas, Wendy Marder, Sara R Till, David A Williams, Chad M Brummett, Neil Basu, Sawsan As-Sanie, Daniel J Clauw,…
Why is there no treatment for osteoarthritis – Opportunity for AI based big data analytics to advance the field
Source: Osteoarthritis and cartilage Authors: F Saxer, G Jansen, S M A Bierma-Zeinstra, B Holzhauer, D Demanse, J Melnick, D Vukadinovic Greetham, T Rall, P Mesenbrink, M Schieker, Publication Date: Sun, 28 Dec 2025 06:00:00 -0500 Osteoarthritis Cartilage. 2025 Dec 26:S1063-4584(25)01291-9. doi: 10.1016/j.joca.2025.12.021. Online ahead…
Self-Perceptions of Aging Mediate the Association Between Chronic Pain and Depression
Source: Pain management nursing : official journal of the American Society of Pain Management Nurses Authors: Bin Ma, Yue Hou, Mengyuan Zhang, Ou Chen, Publication Date: Sat, 27 Dec 2025 06:00:00 -0500 Pain Manag Nurs. 2025 Dec 26:S1524-9042(25)00346-7. doi: 10.1016/j.pmn.2025.12.004. Online ahead of print. ABSTRACT…
Looking Past the Single Diagnosis: Resetting Our Perspective on Pain and Multimorbidity
Source: Pain management nursing : official journal of the American Society of Pain Management Nurses Authors: Jeffrey T Boon, Publication Date: Sat, 27 Dec 2025 06:00:00 -0500 Pain Manag Nurs. 2025 Dec 26:S1524-9042(25)00351-0. doi: 10.1016/j.pmn.2025.12.010. Online ahead of print. NO ABSTRACT PMID:41455661 | DOI:10.1016/j.pmn.2025.12.010 Pubmed…
Psychometric Properties of the Korean King’s Parkinson’s Disease Pain Scale and Its Associations With Clinical Factors and Quality of Life
Source: Pain management nursing : official journal of the American Society of Pain Management Nurses Authors: Yusun Park, Sunyoung Kim, Hui Young So, Sungyang Jo, Hye Young Kim, Jihyun Lee, Sangjin Lee, Sung Reul Kim, Sun Ju Chung, Publication Date: Sat, 27 Dec 2025 06:00:00…
Pediatric Pain Education Research: Text Network Analysis and Topic Modeling
Source: Pain management nursing : official journal of the American Society of Pain Management Nurses Authors: Jinkyung Park, Anna Lee, Namsu Kim, Kyounghae Kim, Publication Date: Sat, 27 Dec 2025 06:00:00 -0500 Pain Manag Nurs. 2025 Dec 26:S1524-9042(25)00339-X. doi: 10.1016/j.pmn.2025.11.021. Online ahead of print. ABSTRACT…