August 1-7, 2025
Showing 1-17 of 17.
Fibromyalgia: do I tackle you with complementary medicines?
Source: Pain reports Authors: Julien Nizard, Françoise Laroche, Fabrice Berna, Publication Date: Fri, 27 Jun 2025 06:00:00 -0400 Pain Rep. 2025 Jun 25;10(4):e1278. doi: 10.1097/PR9.0000000000001278. eCollection 2025 Aug. ABSTRACT Recent guidelines for managing fibromyalgia highlight the importance of a graded-care approach, tailoring treatment to predominant…
Saphenous-sural nerve injury: a sensory-specific rodent model of neuropathic pain without motor deficits
Source: Pain Authors: Po-Yi Paul Su, Liangliang He, Lingyi Zhang, Jessica Yu, Zhonghui Guan, Publication Date: Mon, 04 Aug 2025 06:00:00 -0400 Pain. 2025 Aug 4:10.1097/j.pain.0000000000003722. doi: 10.1097/j.pain.0000000000003722. Online ahead of print. ABSTRACT Clinical neuropathic pain is typically characterized by pain arising from damage or…
Separable dorsal raphe dopamine projections mimic the facets of a loneliness-like state
Source: eLife Authors: Christopher R Lee, Gillian A Matthews, Mackenzie E Lemieux, Elizabeth M Wasserlein, Matilde Borio, Raymundo L Miranda, Laurel R Keyes, Gates P Schneider, Caroline Jia, Andrea Tran, Faith Aloboudi, May G Chan, Enzo Peroni, Grace Pereira, Alba López-Moraga, Anna Pallé, Eyal Y…
Interleukin-4 induces CD11c(+) microglia leading to amelioration of neuropathic pain in mice
Source: eLife Authors: Keita Kohno, Ryoji Shirasaka, Keita Hirose, Takahiro Masuda, Makoto Tsuda, Publication Date: Fri, 01 Aug 2025 06:00:00 -0400 Elife. 2025 Aug 1;14:RP105087. doi: 10.7554/eLife.105087. ABSTRACT Neuropathic pain, a debilitating chronic pain condition, is a major clinical challenge. The pleiotropic cytokine interleukin-4 (IL-4)…
Precise rewiring of corticospinal axons and spinal interneurons via near-infrared optogenetics for spinal cord injury treatment
Source: Science advances Authors: Zhe Ji, Jun Yan, Chenxi Li, Yuhui Sun, Shoupeng Wang, Jin Tao, Jian Liu, Yaobo Liu, Publication Date: Fri, 01 Aug 2025 06:00:00 -0400 Sci Adv. 2025 Aug;11(31):eads4938. doi: 10.1126/sciadv.ads4938. Epub 2025 Aug 1. ABSTRACT To date, precise restoration of proper…
Neuronal Reg3beta/macrophage TNF-alpha-mediated positive feedback signaling contributes to pain chronicity in a rat model of CRPS-I
Source: Science advances Authors: Huimin Nie, Boyu Liu, Chengyu Yin, Zishan Dong, Yushuang Pan, Peiyi Li, Qimiao Hu, Jie Wang, Yan Tai, Xiaomei Shao, Guihua Tian, Chuan Wang, Jianqiao Fang, Boyi Liu, Publication Date: Fri, 01 Aug 2025 06:00:00 -0400 Sci Adv. 2025 Aug;11(31):eadu4270. doi:…
Stimulus contingency and task context encoding within the anterior cingulate-amygdala-cerebellum associative learning network
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience Authors: Jangjin Kim, Hunter E Halverson, John H Freeman, Publication Date: Fri, 01 Aug 2025 06:00:00 -0400 J Neurosci. 2025 Aug 1:e0142252025. doi: 10.1523/JNEUROSCI.0142-25.2025. Online ahead of print. ABSTRACT Cerebellum interactions…
Neuropeptide Y neurons mediate opioid-induced itch by disinhibiting GRP-GRPR microcircuits in the spinal cord
Source: Nature communications Authors: Qian Zeng, Yitong Li, Yifei Wu, Jiawei Wu, Kangtai Xu, Yiming Chen, Yunfei Rao, Nan Li, Yuhui Luo, Changyu Jiang, Chaoran Wu, Zilong Wang, Publication Date: Fri, 01 Aug 2025 06:00:00 -0400 Nat Commun. 2025 Aug 1;16(1):7074. doi: 10.1038/s41467-025-62382-w. ABSTRACT Itch…
Modulatory activity of N-palmitoyl-D-glucosamine in bridging gut dysbiosis and pain mechanisms
Source: Pain Authors: Federica Ricciardi, Andrea Maria Morace, Antimo Fusco, Michela Perrone, Rebecca Limongelli, Stefano Lucà, Marco Montella, Katia Pane, Monica Franzese, Livio Luongo, Marco Salvatore, Sabatino Maione, Francesca Guida, Publication Date: Mon, 04 Aug 2025 06:00:00 -0400 Pain. 2025 Aug 1. doi: 10.1097/j.pain.0000000000003759. Online…
Pain among US adults before, during, and after the COVID-19 pandemic: a study using the 2019 to 2023 National Health Interview Survey
Source: Pain Authors: Anna Zajacova, Hanna Grol-Prokopczyk, Richard L Nahin, Publication Date: Mon, 04 Aug 2025 06:00:00 -0400 Pain. 2025 Aug 5:10.1097/j.pain.0000000000003764. doi: 10.1097/j.pain.0000000000003764. Online ahead of print. ABSTRACT The unprecedented disruption of the COVID-19 pandemic raises crucial questions about its impact on chronic pain…
Pharmacological and genetic approaches to downregulate FIS1 mitigate neuropathic pain
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience Authors: Chang-Lei Zhu, Shu-Jiao Li, Zhi-Peng Lin, Zi-Wei Ni, Ke Tian, Yu-Lu Xia, Jing-Jing Tie, Xue-Yin Pu, Yun-Qiang Huang, Fei-Fei Wu, Hui Liu, Kun-Long Zhang, Shuai Zhang, You-Sheng Wu, Fei Tian,…
Autonomic modulation of pain perception in autism spectrum disorder: unraveling the role of parasympathetic activity among autistic adults
Source: Pain Authors: Merry Kalingel Levi, Eynat Gal, Irit Weissman-Fogel, Tami Bar-Shalita, Tseela Hoffman, Elliot Sprecher, Natalya Yarovinsky, Chen Buxbaum, Yelena Granovsky, Publication Date: Mon, 04 Aug 2025 06:00:00 -0400 Pain. 2025 Aug 4. doi: 10.1097/j.pain.0000000000003750. Online ahead of print. ABSTRACT Autonomic dysfunction in autism…
Ozanimod, a functional sphingosine-1-phosphate receptor 1 antagonist, restores brainstem descending pain pathways in murine models of neuropathic pain
Source: Pain Authors: Luigino Antonio Giancotti, Silvia Squillace, Zhomou Chen, Filomena Lauro, Ying Li, Daniela Salvemini, Publication Date: Mon, 04 Aug 2025 06:00:00 -0400 Pain. 2025 Aug 4. doi: 10.1097/j.pain.0000000000003770. Online ahead of print. ABSTRACT Activation of sphingosine-1-phosphate (S1P) receptor 1 (S1PR1) in the spinal…
Learning the time of pain in the human motor system
Source: Pain Authors: Daniela Dalbagno, Sonia Betti, Sara Garofalo, Vanessa Mannari, Giuseppe di Pellegrino, Francesca Starita, Publication Date: Mon, 04 Aug 2025 06:00:00 -0400 Pain. 2025 Aug 6. doi: 10.1097/j.pain.0000000000003730. Online ahead of print. ABSTRACT Although traditionally conceptualized as a sensory phenomenon, pain could also…
BoNT injection into temporomandibular joint alleviates TMJ pain in forced mouth opening mouse model
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience Authors: Eungyung Kim, Hyeonwi Son, Yan Zhang, John Shannonhouse, Ruben Gomez, Deoksoo Han, Joon Tae Park, Seong Taek Kim, Felix Amarista, Daniel Perez, Edward Ellis, Yu Shin Kim, Publication Date: Mon,…
Distinct nucleus accumbens neural pathways underlie separate behavioral features of chronic pain and comorbid depression
Source: The Journal of clinical investigation Authors: Di Liu, Fang-Xia Xu, Zhuang Yu, Xiao-Jing Huang, Ya-Bing Zhu, Li-Juan Wang, Chen-Wei Wu, Xu Zhang, Jun-Li Cao, Jinbao Li, Publication Date: Mon, 04 Aug 2025 06:00:00 -0400 J Clin Invest. 2025 Aug 1;135(15):e191270. doi: 10.1172/JCI191270. eCollection 2025…
SERBP1-PCIF1 complex-controlled m6Am modification in glutamatergic neurons of the primary somatosensory cortex is required for neuropathic pain in mice
Source: Nature communications Authors: Yue Huang, Gan Ma, Shan Xie, Runa Wei, Ya Liu, Ying Zeng, Yaxuan Zhao, Qihui Wang, Li Yang, Huiying Huang, Lingyun Hao, Xiaotian Zhao, Hongjun Wang, Wen Shen, Stanley Sau Ching Wong, Jun-Li Cao, Yuan-Xiang Tao, Zhi-Qiang Pan, Publication Date: Tue,…