April 24-30, 2026
Showing 1-25 of 43.
Targeting Inflammatory Cell Death: A Strategy for Discogenic Pain Relief
Source: Journal of pain research Authors: Li Wang, Yuheng Zhang, Huaqiang Tao, Chao Jiang, Wenlong Chen, Tianrui Chen, Rui Luo, Yufan Wang, Jinhao Dong, Xiaohan Hu, Weibing Si, Chengyong Gu, Xing Yang, Publication Date: Thu, 30 Apr 2026 06:00:00 -0400 J Pain Res. 2026 Apr…
Tactile perception through fluid-solid interaction
Source: Nature communications Authors: Arman Goshtasbi, Minke Berghuis, Aida Parvaresh, Saravana Prashanth Murali Babu, Robert W Style, Ahmad Rafsanjani, Publication Date: Wed, 29 Apr 2026 06:00:00 -0400 Nat Commun. 2026 Apr 29. doi: 10.1038/s41467-026-72497-3. Online ahead of print. ABSTRACT Soft tactile sensors elevate robotic touch…
Kif15 Orchestrates Neuronal-Microglial Communication via CX3CL1 to Impede Nerve Regeneration
Source: The Journal of biological chemistry Authors: Ronghua Wu, Wei Zhang, Xiaowei Qian, Zhangji Dong, Xiaomei He, Siming Zhang, Taoran Chen, Liu Yang, Yan Liu, Mei Liu, Publication Date: Wed, 29 Apr 2026 06:00:00 -0400 J Biol Chem. 2026 Apr 27:113090. doi: 10.1016/j.jbc.2026.113090. Online ahead…
Neural correlates of perceptual decision-making in the primary somatosensory cortex
Source: Proceedings of the National Academy of Sciences of the United States of America Authors: Alex G Armstrong, Yurii Vlasov, Publication Date: Wed, 29 Apr 2026 06:00:00 -0400 Proc Natl Acad Sci U S A. 2026 May 5;123(18):e2514107123. doi: 10.1073/pnas.2514107123. Epub 2026 Apr 29. ABSTRACT…
Mechanisms and cell type-dependence of non-Hebbian long-term potentiation at primary afferent synapses in the mouse spinal superficial dorsal horn
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience Authors: Jie Li, Mark L Baccei, Publication Date: Tue, 28 Apr 2026 06:00:00 -0400 J Neurosci. 2026 Apr 28:e2082252026. doi: 10.1523/JNEUROSCI.2082-25.2026. Online ahead of print. ABSTRACT Sensory synapses onto ascending spinal…
A positive feedback loop between sensory and octopaminergic neurons underlies nociceptive plasticity in Drosophila larvae
Source: PLoS genetics Authors: Jean-Christophe Boivin, Yi Q Zhao, Jiayi Zhu, Jared T Dakin, Jing Ning, Tomoko Ohyama, Publication Date: Tue, 28 Apr 2026 06:00:00 -0400 PLoS Genet. 2026 Apr 28;22(4):e1012122. doi: 10.1371/journal.pgen.1012122. Online ahead of print. ABSTRACT Adaptive modulation of nociceptive behaviour based on…
AFD thermosensory neurons mediate tactile-dependent locomotion modulation in C. elegans
Source: eLife Authors: Manuel Rosero, Jihong Bai, Publication Date: Mon, 27 Apr 2026 06:00:00 -0400 Elife. 2026 Apr 27;14:RP106496. doi: 10.7554/eLife.106496. ABSTRACT Sensory neurons drive animal behaviors by detecting environmental stimuli and relaying information to downstream circuits. Beyond their primary roles in sensing, these neurons…
A dimmer switch for reward: the vagus sets the gain
Source: Trends in neurosciences Authors: Hongyun Wang, Shuhan Liu, Ling Bai, Publication Date: Sun, 26 Apr 2026 06:00:00 -0400 Trends Neurosci. 2026 Apr 25:S0166-2236(26)00073-1. doi: 10.1016/j.tins.2026.04.002. Online ahead of print. ABSTRACT The vagus nerve, among its various functions, carries gut nutrient signals to brain reward…
Identification of synovial lymphatic system in the temporomandibular joint and their roles in arthritis and pain
Source: Nature communications Authors: Yang Shu, Qing Chang, Ziying Lin, Pao-Fen Ko, Jingyi Chen, Yuyueyang Qiu, Feixiang Chen, Zhen Zhao, Glenn Thomas Clark, Anette Vistoso Monreal, David Ahn, Zhaoyang Liu, Jian Xu, Jian-Fu Chen, Publication Date: Sat, 25 Apr 2026 06:00:00 -0400 Nat Commun. 2026…
Galectins as stress-integrating regulators of neuroimmune signaling and proteinopathy in the central nervous system
Source: Neurobiology of disease Authors: Jian Jing Siew, Yijuang Chern, Publication Date: Sun, 26 Apr 2026 06:00:00 -0400 Neurobiol Dis. 2026 Apr 24;224:107410. doi: 10.1016/j.nbd.2026.107410. Online ahead of print. ABSTRACT Galectins are β-galactoside-binding lectins that play increasingly mechanistic functions in central nervous system (CNS) physiology…
Analgesic, anti-inflammatory and joint protective effects of ACD137, a selective negative allosteric modulator of TrkA, in models of chemotherapy-induced peripheral neuropathy and osteoarthritis
Source: Scandinavian journal of pain Authors: Pontus Forsell, Maria Backlund, Veronica Lidell, Azita Rasti, Cristina Parrado Fernandez, Märta Segerdahl, Johan Sandin, Gunnar Nordvall, Publication Date: Tue, 28 Apr 2026 06:00:00 -0400 Scand J Pain. 2026 Apr 27;26(1). doi: 10.1515/sjpain-2026-0007. eCollection 2026 Jan 1. ABSTRACT OBJECTIVES:…
Potential modulation of pain perception in animal models of acute sleep deprivation: implications of different stress response mechanisms
Source: The journal of headache and pain Authors: Ya Cao, Zhe Yu, Huijian Yuan, Weinan Na, Rongfei Wang, Bozhi Li, Shengyuan Yu, Publication Date: Wed, 29 Apr 2026 06:00:00 -0400 J Headache Pain. 2026 Apr 28. doi: 10.1186/s10194-026-02371-6. Online ahead of print. NO ABSTRACT PMID:42050411…
Dose-dependent dorsal column activation drives analgesic effects of spinal cord stimulation in a rat model of neuropathic pain
Source: Regional anesthesia and pain medicine Authors: Eline M Versantvoort, Kimberley Ladner, Dave Mugan, Darayus Nanavati, Daniel Parker, Quoc C Vuong, Birte E Dietz, Ilona Obara, Publication Date: Wed, 29 Apr 2026 06:00:00 -0400 Reg Anesth Pain Med. 2026 Apr 29:rapm-2026-107607. doi: 10.1136/rapm-2026-107607. Online ahead…
Interrogating the structure and function of the human voltage-gated proton channel hHv1 with a fluorescent noncanonical amino acid
Source: eLife Authors: Emerson M Carmona, William N Zagotta, Sharona E Gordon, Publication Date: Tue, 28 Apr 2026 06:00:00 -0400 Elife. 2026 Apr 28;15:RP110161. doi: 10.7554/eLife.110161. ABSTRACT The human voltage-gated proton channel (hHv1) is a dimer of voltage-sensor domains (VSDs) containing highly selective proton permeation…
Is nociception necessary for pain?
Source: Brain : a journal of neurology Authors: Simon van Rysewyk, Publication Date: Thu, 30 Apr 2026 06:00:00 -0400 Brain. 2026 Apr 30:awag155. doi: 10.1093/brain/awag155. Online ahead of print. Letter to the Editor in response to Weisman et al Brain 2025 “Adieu to an aphorism:…
De novo nitric oxide synthesis drives tactile hypersensitivity induced by ATP-sensitive potassium channel opening in mice: relevance to migraine and other headache disorders
Source: Pain Authors: Rikke Holm Rasmussen, Charlotte Ernstsen, Anja Holm, Sabrina Prehn Lauritzen, Karina Obelitz-Ryom, David Møbjerg Kristensen, Inger Jansen-Olesen, Jes Olesen, Sarah Louise Christensen, Publication Date: Tue, 28 Apr 2026 06:00:00 -0400 Pain. 2026 Apr 29. doi: 10.1097/j.pain.0000000000003955. Online ahead of print. ABSTRACT Adenosine…
Beyond Unconsciousness: Optimizing Antinociception during General Anesthesia
Source: Anesthesiology Authors: Yandong Jiang, Thomas Ledowski, Jamie Sleigh, Publication Date: Wed, 29 Apr 2026 06:00:00 -0400 Anesthesiology. 2026 Apr 29. doi: 10.1097/ALN.0000000000006016. Online ahead of print. ABSTRACT Perioperative analgesia is an essential component of anesthesia, yet the intraoperative management of surgical nociception remains underdiscussed….
Towards a tool to discriminate between pain mechanistic descriptors: expert ranking of clinical features and allocation of weights using a forced choice paradigm
Source: Pain Authors: Muath A Shraim, Michele Sterling, Kathleen A Sluka, Lars Arendt-Nielsen, Miroslav Backonja, Ralf Baron, Vivian Blechschmidt, Daniel J Clauw, Milton Cohen, Brooke K Coombes, Sigrid Elsenbruch, Ian Gilron, Richard E Harris, Lester E Jones, Eleni Kapreli, Fusao Kato, Eva Kosek, Victoria J…
Pharmacist-led migraine consultations in community pharmacies: a pilot study of pharmacists’ experiences and patient-reported outcomes
Source: The journal of headache and pain Authors: Lene Berge Holm, Sahar Hussain, Parisa Gazerani, Tonje Krogstad, Publication Date: Thu, 30 Apr 2026 06:00:00 -0400 J Headache Pain. 2026 Apr 29;27(1):124. doi: 10.1186/s10194-026-02374-3. NO ABSTRACT PMID:42056858 | DOI:10.1186/s10194-026-02374-3 Pubmed ID: pubmed:42056858 Identifiers: pmid:42056858, doi:10.1186/s10194-026-02374-3,
The Veteran Affairs’ Whole Health Approach for Chronic Pain Management: The wHOPE Randomized Clinical Trial
Source: JAMA Authors: Karen H Seal, Benjamin J Morasco, Aaron M Martin, Kavitha P Reddy, Theresa M Van Iseghem, Rendelle E Bolton, Barbara G Bokhour, Jennifer Murphy, Lauren M Denneson, Denise Esserman, Eugenia Buta, Natalie Purcell, Daniel Bertenthal, Jacob T Painter, Linda R Abadjian, Liliana…
Pain sensitivity following a standardized two-hour cycling session: a randomized controlled crossover Study
Source: Scandinavian journal of pain Authors: Fabian Tomschi, Joschua Wiese, Holger Stephan, Thomas Hilberg, Publication Date: Tue, 28 Apr 2026 06:00:00 -0400 Scand J Pain. 2026 Apr 27;26(1). doi: 10.1515/sjpain-2025-0045. eCollection 2026 Jan 1. ABSTRACT OBJECTIVE: Exercise induced hypoalgesia (EIH) is characterized by an acute…
Translation, cross-cultural adaptation, and preliminary psychometric evaluation of the Urdu BackPAQ, pain resilience scale, and medical imaging beliefs questionnaire in adults with low back pain
Source: Scandinavian journal of pain Authors: Muhammad Naseeb Ullah Khan, Aastha Malhotra, Melainie Cameron, Publication Date: Wed, 29 Apr 2026 06:00:00 -0400 Scand J Pain. 2026 Apr 28;26(1). doi: 10.1515/sjpain-2026-0001. eCollection 2026 Jan 1. ABSTRACT OBJECTIVES: Low back pain (LBP) is the leading cause of…
The impact of spinal pain on family members’ burden: a cross-sectional study
Source: Scandinavian journal of pain Authors: Casper Nim, Pernille Platz Skrubbeltrang, Peter Måhr, Henrik Hein Lauridsen, Publication Date: Wed, 29 Apr 2026 06:00:00 -0400 Scand J Pain. 2026 Apr 28;26(1). doi: 10.1515/sjpain-2026-0005. eCollection 2026 Jan 1. ABSTRACT OBJECTIVE: Spinal pain is highly prevalent and associated…
Reduced versus standard dosing of Janus kinase inhibitors in rheumatoid arthritis: a propensity score-matched real-world study accounting for poor prognostic factors
Source: Annals of the rheumatic diseases Authors: Yuji Nozaki, Toshihiko Shiga, Jinhai Ri, Tetsu Itami, Daisuke Tomita, Hirotaka Yamazawa, Yumi Morimoto, Rika Fukuda, Takashi Tsuchimoto, Sayo Morita, Hiroki Akazawa, Koichi Murata, Akira Onishi, Kosuke Ebina, Iku Shirasugi, Hirotaka Yamada, Motomu Hashimoto, Ryu Watanabe, Yumiko Wada,…
The mechanism of different microglial receptors mediating central inflammation in chronic migraine: a meta-analysis
Source: The journal of headache and pain Authors: Xinyu Lin, Wenjing Yu, Jiafei Lou, Zhijian Cao, Wenwen Song, Publication Date: Mon, 27 Apr 2026 06:00:00 -0400 J Headache Pain. 2026 Apr 27;27(1):122. doi: 10.1186/s10194-026-02372-5. ABSTRACT BACKGROUND: Microglial activation is increasingly recognized as a critical contributor…