On March 18, William Maixner, University of North Carolina at Chapel Hill, US, gave a talk on what the present and future look like for personalized pain medicine. After his talk, there was a panel discussion featuring:
- Michael Costigan, Boston Children's Hospital, US
- Robert Dworkin, University of Rochester School of Medicine and Dentistry, US
- David Bennett, University of Oxford, UK (moderator)
Watch the webinar recording below.
This is how Maixner describes his talk:
Persistent pain conditions frequently overlap and are either untreated or undertreated, since their pathophysiologic origins are largely unknown, and standard therapies have limited effect. In many respects, this represents a silent or hidden epidemic. We are learning more about chronic pain conditions, including that they appear to resemble a mosaic of phenotypes that are further influenced by genetic factors and/or environmental events and exposures. Continued investigation is needed to increase understanding of the complex mechanisms underlying these conditions and the role of biomarkers that trigger them.
In this webinar, he presented the following:
- A heuristic model that integrates putative risk factors and domains associated with complex persistent pain conditions.
- Studies based on reverse translational approaches, leading to: 1) diagnostic/prognostic algorithms, and 2) new pharmacotherapeutics: targets and drugs.
“Personalized Pain Medicine: Improving Diagnosis and Treatment of Complex Persistent Pain Conditions” is the sixth in a new series of PRF webinars supported by Genentech and MedImmune, with additional site support from other PRF sponsors. All webinars and other site content on PRF are editorially independent; all editorial decisions are made solely by the PRF editors. See previous PRF webinars here.